Non-Cochrane · aetiology · PM37972211
Is there an association between periodontal disease and root caries? A systematic review and meta-analysis.
Nazário Rayssa Maitê Farias, Frazão Deborah Ribeiro, Peinado Beatriz Rodrigues Risuenho, et al. · PloS one · 2023 · PubMed · doi:10.1371/journal.pone.0285955
Full textEvery question was extracted from the full text, figures and supplements by two independent LLM extractors, disagreements adjudicated. Rows cite where in the review the value comes from.
Questions
1
current version
GRADE rated
1
No studies
0
Included studies
4
linked below
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Adult patients | Adults (4 studies; 18,724 participants total; mean age ~53 years; China, England, Japan, Finland) |
| Intervention | Periodontal disease (periodontitis, gingival disease) as exposure | Periodontal disease by clinical exam (CAL, pocket depth, gingival inflammation, BPE) (n=4 studies) |
| Comparison | Adults without periodontal disease (healthy periodontal status) | Participants without periodontal disease / healthy periodontal status (2 studies pooled: periodontal disease n=3677 vs control n=3987) |
| Outcomes | Root caries | Root caries (assessed by RCI, root DMFT/DFT indices); pooled OR 1.38 (1.25-1.53) |
| Study designs | Prospective or retrospective observational studies (PECO) | 4 observational (cross-sectional) studies; 2 entered the meta-analysis |
| Timing | Not specified (no year restriction) | Cross-sectional (single time point) |
Search date: April 2023 (searches updated until April 2023). Databases: Cochrane Library; LILACS; MedLine (via PubMed); Scopus; Web of Science; Google Scholar; Open Grey (grey literature)
Questions and results
Periodontal disease (periodontitis; clinical attachment loss >=4 mm) vs Adults without periodontal disease (healthy periodontal status; CAL <=3 mm)
Population: Adults (mean age ~53 years)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Root caries (presence of root caries) Adults with periodontal disease had significantly higher odds of root caries than those without (pooled OR 1.38, 95% CI 1.25 to 1.53; 2 observational studies; low certainty). Source: Fig 2 (forest plot); Table 6 (GRADE evidence profile); Results 'Data synthesis and meta-analysis' and 'Certainty of evidence'; Abstract · same question in other reviews | OR 1.38 [1.25, 1.53] | 2 studies · 7664 participants | Low |
Included primary studies 4
Open as a trial list| Study | Also included by | Outcomes it informs here | Trial PICO | Results |
|---|---|---|---|---|
| Yu et al. 2021 The relationship between different types of caries and periodontal disease severity in middle-aged and elderly people: findings from the… PMID:33941169 | 1 other review | Root caries (presence of root caries) | not extracted yet | not extracted yet |
| AlQobaly & Sabbah 2020 The association between periodontal disease and root/coronal caries DOI:10.1111/idh.12422 | this review only | Root caries (presence of root caries) | not extracted yet | not extracted yet |
| Saotome et al. 2006 Relationship of cariogenic bacteria levels with periodontal status and root surface caries in elderly Japanese DOI:10.1111/j.1741-2358.2006.00127.x | this review only | Root caries (presence of root caries) | not extracted yet | not extracted yet |
| Vehkalahti & Paunio 1994 Association between Root Caries Occurrence and Periodontal State DOI:10.1159/000261990 | this review only | Root caries (presence of root caries) | not extracted yet | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match).
| Review | Shared studies | Jaccard |
|---|---|---|
| Association between periodontitis and dental caries: a systematic review and meta-analysis. (2024) | 1 | 0.03 |