Question · asked by 1 review

Illicit drug use vs People who do not use drugs: Periodontal disease

Population
People who use drugs (PWUD): methamphetamine, heroin, opiate, cannabis and cocaine users
Intervention
Illicit drug use
Comparison
People who do not use drugs
Outcome
Periodontal disease

Illicit drug use was not significantly associated with periodontal disease (pooled OR 1.44, 95% CI 0.80-2.60; 5 studies; substantial heterogeneity I2=85%; ungraded).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Illicit drug use vs People who do not use drugs
Periodontal disease · People who use drugs (PWUD): methamphetamine, heroin, opiate, cannabis and cocaine users · High-income countries (USA, Germany, New Zealand, Saudi Arabia) and India; studies 2008-2016
Illicit drug use was not significantly associated with periodontal disease (pooled OR 1.44, 95% CI 0.80-2.60; 5 studies; substantial heterogeneity I2=85%; ungraded).
Dental caries and periodontal disease among people who use drugs: a systematic review and meta-analysis. (2020) All outcomes
OR 1.44 [0.80, 2.60]5 studiesGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Dental caries and periodontal disease among people who use drugs: a systematic review and meta-analysis.
2020 All outcomes
Before 1 July 201910Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.