Hypertension · Adults (general population)
Meta-analysis of observational studies (higher vs lower 25(OH)D) for Hypertension: RR 0.70 (95% CI 0.58 to 0.86), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
Treatment failure Need to intensify therapy/ED or hospital admission · exacerbations of COPD
Systemic corticosteroid leads to lower treatment failure Need to intensify therapy/ED or hospital admission compared with placebo (high certainty).
1 finding from 1 review
Treatment failure Need for additional treatment · exacerbations of COPD
Treatment route: intravenous corticosteroid showed no clear difference in treatment failure Need to intensify therapy compared with oral corticosteroid (moderate certainty).
1 finding from 1 review
Smoking cessation at time of surgery ‐ Intensive behavioural intervention (multiple contacts, initiated at least 4 weeks before surgery) · People awaiting surgery
Behavioural intervention probably leads to higher smoking cessation at time of surgery ‐ Intensive behavioural… compared with control (moderate certainty).
1 finding from 1 review
Postoperative morbidity: Any complication ‐ Intensive intervention · People awaiting surgery
Behavioural intervention probably leads to lower postoperative morbidity: Any complication ‐ Intensive intervention compared with control (moderate certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Patients with osteoarthritis of the knee or hip
Oral or transdermal opioids showed no clear difference in pain intensity Various pain scales. (median compared with placebo (high certainty).
1 finding from 1 review
Intervention not reported
Numbers of adverse effects due to hypertension · patients with the anaemia of end‐stage kidney disease undergoing dialysis
The intervention showed no clear difference in numbers of adverse effects due to hypertension (high certainty).
1 finding from 1 review
Hypertension · patients with the anaemia of end‐stage kidney disease undergoing dialysis
1 finding from 1 review
Adverse events: hypertension · patients with the anaemia of end‐stage kidney disease undergoing dialysis
1 finding from 1 review
Adverse events: hypertension · patients with the anaemia of end‐stage kidney disease undergoing dialysis
CERA showed no clear difference in numbers of adverse events due to hypertension: CERA every 2 weeks… compared with other ESA (high certainty).
1 finding from 1 review
Intervention not reported
Presence of PHN 6 months after the onset of the acute herpetic rash2 Clinical diagnostic criteria for PHN in any intensity · people with acute herpes zoster1
1 finding from 1 review
Intervention not reported
Presence of PHN 4 months after the onset of the acute herpetic rash Clinical diagnostic criteria for PHN in any intensity · people with acute herpes zoster1
The intervention showed no clear difference in presence of PHN 4 months after the onset of the acute herpetic rash… (high certainty).
1 finding from 1 review
Nipple pain 5‐point verbal descriptor scale · breastfeeding women with sore nipples
2 findings from 1 review
Training intensity: fInal training session (% baseline peak work capacity) · patients with chronic obstructive pulmonary disease
1 finding from 1 review
Mortality and morbidity prior to discharge (Neonatal intensive care admissions) · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks
Antibiotic showed no clear difference in mortality and morbidity prior to discharge (Neonatal intensive care… compared with placebo (low certainty).
1 finding from 1 review
Duration of admission to neonatal intensive care unit · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intensive care unit length of stay (based on type of control arm): predominantly protocolized control strategy · patients with weaning time in invasively ventilated critically ill adults
1 finding from 1 review
Intensive care unit length of stay (based on type of control arm): predominantly non‐protocolized control strategy · patients with weaning time in invasively ventilated critically ill adults
1 finding from 1 review
Reduction in pain score: distension of painful pelvic structures versus counselling · women with chronic pelvic pain
1 finding from 1 review
no estimate extracted
48 participants
Moderate
Intervention not reported
Hypotension · children (aged < 18 years) with acute severe pain
1 finding from 1 review