Cochrane · systematic review · CD007366

Interventions for treating painful nipples among breastfeeding women

Dennis, CL, Jackson, K, Watson, J · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
15
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 12 · 80%Moderate 3 · 20%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Glycerine gel dressing versus usual care

Population: breastfeeding women with sore nipples
1 question
OutcomeEffectEvidenceStatus / GRADE
Nipple pain Nipple trauma: midwife assessed based on scale of 1‐3 with: 1 = better/resolved, 2 = no change, and 3 = worse
Glycerine gel dressing vs usual care
no estimate extracted1 study · 63 participantsLow
Downgraded: risk of bias, imprecision

Breast shells with lanolin versus usual care

Population: breastfeeding women with sore nipples
1 question
OutcomeEffectEvidenceStatus / GRADE
Nipple pain 5‐point Likert scale with established test‐re‐test reliability
Breast shells with lanolin vs usual care
no estimate extracted1 study · 61 participantsLow
Downgraded: risk of bias, imprecision

Glycerine gel dressing versus breast shells with lanolin

Population: breastfeeding women with sore nipples
1 question
OutcomeEffectEvidenceStatus / GRADE
Nipple pain 5‐point Likert scale with established test‐re‐test reliability
Glycerine gel dressing vs breast shells with lanolin
no estimate extracted1 study · 64 participantsLow
Downgraded: risk of bias, imprecision

Lanolin versus no intervention (control group)

Population: breastfeeding women with sore nipples
3 questions
OutcomeEffectEvidenceStatus / GRADE
Nipple pain 5‐point verbal descriptor scale
Lanolin vs no intervention (control group)
RR 0.97 [0.91, 1.04]1 study · 147 participantsLow
Downgraded: risk of bias, imprecision
Nipple pain 5‐point verbal descriptor scale
Lanolin vs no intervention (control group)
RR 1.3 [0.63, 2.66]2 studies · 312 participantsLow
Nipple pain 5‐point verbal descriptor scale
Lanolin vs no intervention (control group)
RR 0.85 [0.63, 1.14]2 studies · 297 participantsLow

Expressed breast milk versus no intervention (control group)

Population: breastfeeding women with sore nipples
3 questions
OutcomeEffectEvidenceStatus / GRADE
Nipple pain 5‐point verbal descriptor scale
Expressed breast milk vs no intervention (control group)
RR 0.96 [0.9, 1.03]1 study · 151 participantsLow
Downgraded: risk of bias, imprecision
Nipple pain 5‐point verbal descriptor scale
Expressed breast milk vs no intervention (control group)
RR 1.17 [0.71, 1.92]1 study · 151 participantsLow
Downgraded: risk of bias, imprecision
Nipple pain 5‐point verbal descriptor scale
Expressed breast milk vs no intervention (control group)
RR 0.62 [0.11, 3.63]1 study · 151 participantsLow
Downgraded: risk of bias, imprecision

Lanolin versus expressed breast milk

Population: breastfeeding women with sore nipples
3 questions
OutcomeEffectEvidenceStatus / GRADE
Nipple pain Women's reports of 'absence of irritation'
Lanolin vs expressed breast milk
RR 1.01 [0.93, 1.09]1 study · 152 participantsLow
Downgraded: risk of bias, imprecision
Nipple pain Women's reports of 'absence of irritation'
Lanolin vs expressed breast milk
RR 1.56 [1.05, 2.32]1 study · 152 participantsLow
Downgraded: risk of bias, imprecision
Nipple pain Women's reports of 'absence of irritation'
Lanolin vs expressed breast milk
RR 1.58 [0.27, 9.2]1 study · 152 participantsLow
Downgraded: risk of bias, imprecision

Lanolin versus all‐purpose nipple ointment

Population: breastfeeding women with sore nipples
3 questions
OutcomeEffectEvidenceStatus / GRADE
Nipple pain Short Form McGill Pain Questionnaire scale 0‐45
Lanolin vs all‐purpose nipple ointment
no estimate extracted1 study · 150 participantsModerate
Downgraded: imprecision
Nipple pain Present Pain Intensity scale 0‐5
Lanolin vs all‐purpose nipple ointment
no estimate extracted1 study · 150 participantsModerate
Downgraded: imprecision
Nipple pain Present Pain Intensity scale 0‐10
Lanolin vs all‐purpose nipple ointment
no estimate extracted1 study · 150 participantsModerate
Downgraded: imprecision