Cochrane · systematic review · CD009942
Intranasal fentanyl for the management of acute pain in children
Murphy, A, O'Sullivan, R, Wakai, A, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 66.7%High 2 · 33.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: children (aged < 18 years) with acute severe pain
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain reduction (mean VAS) Pain assessed before analgesia (0 min) and at 5, 10, 20 and 30 min after analgesia | no estimate extracted | 1 study · 67 participants | High |
Respiratory depression | no estimate extracted | 1 study · 67 participants | Moderate |
Hypotension | no estimate extracted | 1 study · 67 participants | Moderate |
Decreased level of consciousness | no estimate extracted | 1 study · 67 participants | Moderate |
Intolerance to analgesia | no estimate extracted | 1 study · 67 participants | High |
Use of ED "rescue" analgesia | no estimate extracted | 1 study · 67 participants | Moderate |