Cochrane · systematic review · CD006866

Antiviral treatment for preventing postherpetic neuralgia

Chen, N, Li, Q, Yang, J, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 3 · 100%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Oral aciclovir for acute herpes zoster to prevent postherpetic neuralgia (PHN)

Population: people with acute herpes zoster1
3 questions
OutcomeEffectEvidenceStatus / GRADE
Presence of PHN 6 months after the onset of the acute herpetic rash2 Clinical diagnostic criteria for PHN in any intensity
no estimate extracted2 studies · 476 participantsHigh
Presence of PHN 4 months after the onset of the acute herpetic rash Clinical diagnostic criteria for PHN in any intensity
RR 0.75 [0.51, 1.11]3 studies · 609 participantsHigh
Adverse events Clinical manifestations
RR 1.01 [0.88, 1.15]4 studies · 709 participantsHigh