Oral or transdermal opioids vs placebo: Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale)
Oral or transdermal opioids showed no clear difference in pain intensity Various pain scales. (median compared with placebo (high certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Oral or transdermal opioids vs placebo Pain intensity Various pain scales. (median · participants with osteoarthritis of the knee or hip Oral or transdermal opioids showed no clear difference in pain intensity Various pain scales. (median compared with placebo (high certainty). Oral or transdermal opioids for osteoarthritis of the knee or hip (2014) · Cochrane Headline outcomes only | no estimate extracted | 22 studies · 8275 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral or transdermal opioids for osteoarthritis of the knee or hip 2014 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.