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Evidence found and GRADE certainty

2,661 questions · 2,751 findings · 453 reviews

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No studies found 593 · 21.6%GRADE not reported 277 · 10.1%Very low 538 · 19.6%Low 712 · 25.9%Moderate 516 · 18.8%High 115 · 4.2%

BRIEF FAMILY INTERVENTION vs usual care

Hospital admissions · patients with schizophrenia

It is very uncertain whether BRIEF FAMILY INTERVENTION changes service utilisation ‐ hospital admission ‐ medium to long term… compared with STANDARD CARE (very low certainty).

1 finding from 1 review

BRIEF FAMILY INTERVENTION vs usual care

Global state: relapse ‐ medium term ‐ not measured · patients with schizophrenia

BRIEF FAMILY INTERVENTION showed no clear difference in global state ‐ relapse ‐ medium to long term relapse rates (clinical… compared with STANDARD CARE (low certainty).

1 finding from 1 review

Glutamine‐supplemented nutrition vs non‐supplemented nutrition

Long‐term mortality (closest to six month) · critically ill patients or receiving major surgery

Glutamine‐supplemented nutrition showed no clear difference in long‐term mortality (closest to six month) compared with non‐supplemented nutrition (moderate certainty).

1 finding from 1 review

Combination of manual therapy, exercise, electrotherapy and oral NSAID vs oral NSAID

Adverse events Pain persisting longer than 2 hours after treatment (during the 3‐week treatment period) · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy, exercise, electrotherapy and oral NSAID may leads to higher adverse events Pain persisting longer than 2 hours after treatment… compared with oral NSAID (low certainty).

1 finding from 1 review

Intervention not reported

Achieved recovery according to predetermined criteria (no longer meeting criteria for depression on K‐SADS or meeting a priori criteria for response on a depression checklist, assessed between 4 and 10 weeks of onset of treatment) · children and adolescents with depression

The intervention showed no clear difference in achieved recovery according to predetermined criteria (no longer… (low certainty).

1 finding from 1 review

Exercise vs control

Symptoms of depression (long‐term) different scales · depression in adults
1 finding from 1 review
  • Exercise for depression 2013 · Cochrane Headline outcomes only
    no estimate extracted
    8 studies · 377 participants
    Low

Posterior cruciate ligament retention vs sacrifice (using the same arthroplasty design)

Re‐operation rate (not involving implant change, short and long term) · Patients receiving total knee arthroplasty with or without resection of the posterior cruciate ligament for the treatment of osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Posterior cruciate ligament retention vs posterior stabilised sacrifice

Re‐operation rate (not involving implant change, short and long term) · Patients receiving total knee arthroplasty with or without posterior stabilised design for the treatment of osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Posterior cruciate ligament retention vs sacrifice (all types of arthroplasty designs)

Re‐operation rate (not involving implant change, short and long term) · Patients receiving total knee arthroplasty with or without posterior stabilised design for the treatment of osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

ANY INTERMITTENT DRUG TECHNIQUE vs MAINTENANCE THERAPY

Relapse · patients with schizophrenia

ANY INTERMITTENT DRUG TECHNIQUE probably leads to higher relapse: long term (+ 26 weeks) as defined in each study compared with MAINTENANCE THERAPY (moderate certainty).

2 findings from 1 review