Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

75,239 questions in 5,342 reviews

current versions
No studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Studies focused only on enhanced communication, without clarification of values and preferences, vs control
Knowledge of all the options*** · women aged 40 to 75 years old at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
MD 1.14 [0.61, 1.62]4 studies · 2510 participantsHigh
Studies focused only on enhanced communication, without clarification of values and preferences, vs control
Adherence to the chosen option · women aged 40 to 75 years old at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
no estimate extractedNRNo studies
Studies focused only on enhanced communication, without clarification of values and preferences, vs control
Choice of an option aligned with each woman’s values and preferences · women aged 40 to 75 years old at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
no estimate extractedNRNo studies
Shared decision‐making (all components) vs control
Confidence in the decision made · women aged 40 to 75 years at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
no estimate extractedNRNo studies
Studies focused only on enhanced communication, without clarification of values and preferences, vs control
Woman's involvement · women aged 40 to 75 years old at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
no estimate extractedNRNo studies
Studies focused only on enhanced communication, without clarification of values and preferences, vs control
Mental health outcomes · women aged 40 to 75 years old at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
MD 0.332 studies · 1193 participantsHigh
Shared decision‐making (all components) vs control
Knowledge of all the options · women aged 40 to 75 years at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
RR 1.18 [0.61, 2.28]1 study · 133 participantsVery low
Shared decision‐making (all components) vs control
Adherence to the chosen option · women aged 40 to 75 years at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
no estimate extractedNRNo studies
Shared decision‐making (all components) vs control
Choice of an option aligned with each woman’s values and preferences · women aged 40 to 75 years at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
no estimate extractedNRNo studies
Shared decision‐making (all components) vs control
Woman's involvement · women aged 40 to 75 years at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
no estimate extractedNRNo studies
Shared decision‐making (all components) vs control
Mental health outcomes · women aged 40 to 75 years at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
no estimate extractedNRNo studies
Some components of shared decision‐making, including clarification of values and preferences, vs control
Satisfaction with the decision‐making process · women aged 38 to 71 years at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
no estimate extractedNRNo studies
Some components of shared decision‐making, including clarification of values and preferences, vs control
Confidence in the decision made · women aged 38 to 71 years at average to moderate risk of breast cancer
Shared decision‐making for supporting women’s decisions about breast cancer screening (2024) · Cochrane
no estimate extracted4 studies · 1714 participantsVery low
Summary of findings table ‐ Vitamin B12 supplementation vs placebo/no vitamin B12 supplementation
Maternal anaemia · pregnant women
Vitamin B12 supplementation during pregnancy for maternal and child health outcomes (2024) · Cochrane
RR 1.08 [0.93, 1.26]2 studies · 284 participantsVery low
Summary of findings table ‐ Vitamin B12 supplementation vs placebo/no vitamin B12 supplementation
Maternal vitamin B12 deficiency · pregnant women
Vitamin B12 supplementation during pregnancy for maternal and child health outcomes (2024) · Cochrane
RR 0.38 [0.28, 0.51]2 studies · 272 participantsVery low
Summary of findings table ‐ Vitamin B12 supplementation vs placebo/no vitamin B12 supplementation
Spontaneous abortion or miscarriage · pregnant women
Vitamin B12 supplementation during pregnancy for maternal and child health outcomes (2024) · Cochrane
no estimate extracted2 studies · 448 participantsVery low
Summary of findings table ‐ Vitamin B12 supplementation vs placebo/no vitamin B12 supplementation
Low birthweight (< 2500 g) · pregnant women
Vitamin B12 supplementation during pregnancy for maternal and child health outcomes (2024) · Cochrane
RR 1.5 [0.93, 2.43]2 studies · 334 participantsLow
Summary of findings table ‐ Vitamin B12 supplementation vs placebo/no vitamin B12 supplementation
Preterm birth (< 37 weeks) · pregnant women
Vitamin B12 supplementation during pregnancy for maternal and child health outcomes (2024) · Cochrane
RR 0.97 [0.55, 1.74]2 studies · 340 participantsLow
Summary of findings table ‐ Vitamin B12 supplementation vs placebo/no vitamin B12 supplementation
Child cognitive outcomes · pregnant women
Vitamin B12 supplementation during pregnancy for maternal and child health outcomes (2024) · Cochrane
no estimate extracted1 study · 178 participantsLow
Summary of findings table ‐ Vitamin B12 supplementation vs placebo/no vitamin B12 supplementation
Neural tube defects ‐ not reported · pregnant women
Vitamin B12 supplementation during pregnancy for maternal and child health outcomes (2024) · Cochrane
no estimate extractedNRNo studies
Intrauterine injection of autologous platelet‐rich plasma vs no intervention
Live birth (or ongoing pregnancy) · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 1.1 [0.38, 3.14]1 study · 94 participantsVery low
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Adverse events: preterm delivery · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 8.02 [1.72, 37.33]1 study · 120 participantsLow
Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor
Live birth (or ongoing pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 0.88 [0.43, 1.81]1 study · 132 participantsVery low
Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor
Miscarriage · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 1.94 [0.63, 5.96]1 study · 132 participantsVery low
Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor
Clinical pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 1.24 [0.66, 2.35]2 studies · 172 participantsVery low
Intrauterine infusion of autologous platelet‐rich plasma vs intrauterine infusion of granulocyte colony‐stimulating factor
Adverse events · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
no estimate extractedNRNo studies
Intraovarian injection of autologous platelet‐rich plasma vs no intervention
Ongoing pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 1.09 [0.33, 3.63]1 study · 73 participantsVery low
Intraovarian injection of autologous platelet‐rich plasma vs no intervention
Miscarriage · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
no estimate extractedNRNo studies
Intraovarian injection of autologous platelet‐rich plasma vs no intervention
Clinical pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 0.9 [0.31, 2.6]1 study · 73 participantsVery low
Intraovarian injection of autologous platelet‐rich plasma vs no intervention
Adverse events · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
no estimate extractedNRNo studies
Intrauterine injection of autologous platelet‐rich plasma vs no intervention
Miscarriage · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 0.96 [0.13, 7.09]1 study · 94 participantsVery low
Intrauterine injection of autologous platelet‐rich plasma vs no intervention
Clinical pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 1.55 [0.64, 3.76]1 study · 94 participantsVery low
Intrauterine injection of autologous platelet‐rich plasma vs no intervention
Adverse events: ectopic pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 2.94 [0.12, 73.95]1 study · 94 participantsVery low
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Live birth (or ongoing pregnancy) · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 2.38 [1.16, 4.86]6 studies · 564 participantsVery low
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Miscarriage · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 1.54 [0.59, 4.01]5 studies · 504 participantsVery low
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Clinical pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 2.22 [1.5, 3.27]9 studies · 824 participantsVery low
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Adverse events: multiple pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 2.68 [0.81, 8.88]2 studies · 240 participantsVery low
Intrauterine infusion/injection of autologous platelet‐rich plasma vs no intervention or placebo
Adverse events: ectopic pregnancy · women undergoing assisted reproduction
Autologous platelet‐rich plasma for assisted reproduction (2024) · Cochrane
OR 2.94 [0.12, 73.95]1 study · 94 participantsVery low
Summary of findings: Any alternative model of care vs usual care
Emergency department (ED) visits: proportion of residents with at least one ED visit at longest · residents of aged care facilities
Models for delivery and co‐ordination of primary or secondary health care (or both) to older adults living… (2024) · Cochrane
RR 1.01 [0.84, 1.2]7 studies · 1276 participantsLow
Summary of findings: Any alternative model of care vs usual care
Unplanned hospital admissions: proportion of residents with at least one unplanned hospital admission at longest · residents of aged care facilities
Models for delivery and co‐ordination of primary or secondary health care (or both) to older adults living… (2024) · Cochrane
RR 0.74 [0.56, 0.99]8 studies · 1263 participantsLow
Summary of findings: Any alternative model of care vs usual care
Adverse events/falls: proportion of residents with a fall at longest · residents of aged care facilities
Models for delivery and co‐ordination of primary or secondary health care (or both) to older adults living… (2024) · Cochrane
RR 1.15 [0.83, 1.6]3 studies · 1061 participantsVery low
Summary of findings: Any alternative model of care vs usual care
Adherence to clinical guideline‐recommended care: proportion of residents with adequate antidepressant therapy at longest · residents of aged care facilities
Models for delivery and co‐ordination of primary or secondary health care (or both) to older adults living… (2024) · Cochrane
RR 5.29 [1.08, 26]1 study · 65 participantsVery low
Summary of findings: Any alternative model of care vs usual care
Health‐related quality of life (mean difference) at longest · residents of aged care facilities
Models for delivery and co‐ordination of primary or secondary health care (or both) to older adults living… (2024) · Cochrane
MD 0.01612 studies · 4016 participantsLow
Summary of findings: Any alternative model of care vs usual care
Mortality: proportion of residents who died at longest · residents of aged care facilities
Models for delivery and co‐ordination of primary or secondary health care (or both) to older adults living… (2024) · Cochrane
RR 1.03 [0.92, 1.16]24 studies · 3881 participantsModerate
Summary of findings: Any alternative model of care vs usual care
Resource use: cost‐effectiveness evaluations (6 to 21 months) · residents of aged care facilities
Models for delivery and co‐ordination of primary or secondary health care (or both) to older adults living… (2024) · Cochrane
no estimate extracted5 studies · 2341 participantsVery low
Summary of findings table ‐ Psychosocial intervention vs control
Mental well‐being at study endpoint · promoting the mental health of people living in LMICs affected by humanitarian crises (children)
Psychological and social interventions for the promotion of mental health in people living in low‐ and… (2024) · Cochrane
no estimate extracted3 studies · 3378 participantsVery low
Summary of findings table ‐ Psychosocial intervention vs control
Functioning at · promoting the mental health of people living in LMICs affected by humanitarian crises (adults)
Psychological and social interventions for the promotion of mental health in people living in low‐ and… (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Psychosocial intervention vs control
Prosocial behaviour at study endpoint ‐ not measured · promoting the mental health of people living in LMICs affected by humanitarian crises (adults)
Psychological and social interventions for the promotion of mental health in people living in low‐ and… (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Psychosocial intervention vs control
Prosocial behaviour at · promoting the mental health of people living in LMICs affected by humanitarian crises (adults)
Psychological and social interventions for the promotion of mental health in people living in low‐ and… (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Psychosocial intervention vs control
Mental well‐being at · promoting the mental health of people living in LMICs affected by humanitarian crises (children)
Psychological and social interventions for the promotion of mental health in people living in low‐ and… (2024) · Cochrane
no estimate extracted1 study · 258 participantsVery low