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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

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No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Fresh vs frozen embryo transfers

Small for gestational age (birth weight below 10th percentile): after first ET · women undergoing assisted reproduction

It is very uncertain whether fresh changes small for gestational age (birth weight below 10th percentile):… compared with frozen embryo transfers (very low certainty).

1 finding from 1 review

iron‐fortified wheat flour with or without other micronutrients added vs fortified wheat flour with same micronutrients (but not iron)

Anaemia · general population of all age groups (including pregnant women) from any country, over two years of age

iron‐fortified wheat flour with or without other micronutrients added may leads to lower anaemia (defined as haemoglobin below WHO cut‐off for age and… compared with wheat flour (no added iron) with the same other micronutrients added (low certainty).

1 finding from 1 review

Wheat flour fortified with iron in combination with other micronutrients vs unfortified wheat flour (no micronutrients added)

Anaemia · general population of all age groups (including pregnant women) from any country, over two years of age

It is very uncertain whether iron‐fortified wheat flour with other micronutrients added changes anaemia (defined as haemoglobin below WHO cut‐off for age and… compared with unfortified wheat flour (no micronutrients added) (very low certainty).

1 finding from 1 review

Chloral hydrate oral (100 mg/kg or 75 mg/kg) vs midazolam

Proportion of children with inadequate level of sedation (Ramsay score below 4) · children undergoing neurodiagnostic procedures

Chloral hydrate oral (100 mg/kg or 75 mg/kg) probably leads to lower proportion of children with inadequate level of sedation (Ramsay… compared with midazolam (intranasal 0.2 mg/kg or oral 0.5 mg/kg) (moderate certainty).

1 finding from 1 review

Chloral hydrate oral (70 mg/kg) vs promethazine

Proportion of children with inadequate level of sedation (Ramsay score below 4) · children undergoing neurodiagnostic procedures

Chloral hydrate oral (70 mg/kg) may leads to lower proportion of children with inadequate level of sedation (Ramsay… compared with promethazine oral (1 mg/kg) (low certainty).

1 finding from 1 review