Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Intervention not reported

Parasitological failure Method: stool microscopy demonstrating E histolytica cysts or trophozoites · adults and children with amoebic colitis

The intervention showed no clear difference in parasitological failure Method: stool microscopy demonstrating E… (low certainty).

1 finding from 1 review

Intervention not reported

Parasitological failure 1 to 14 days after end of treatment Method: stool microscopy demonstrating E histolytica cysts or trophozoites · adults and children with amoebic colitis

The intervention may leads to lower parasitological failure 1 to 14 days after end of treatment Method:… (low certainty).

1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Patient dissatisfaction with the cosmetic result at 1 yearh · adults with acute acromioclavicular dislocation of the shouldera

It is very uncertain whether surgical intervention changes patient dissatisfaction with the cosmetic result at 1 yearh compared with conservative intervention (very low certainty).

1 finding from 1 review

Amifostine vs no otoprotective intervention

Ototoxicity according to NCI CTC v2 criteria with intra‐arterial platinum (combined asymptomatic and symptomatic disease) Exact test method not reported · children with cancer treated with platinum‐based therapy

Amifostine showed no clear difference in ototoxicity according to NCICTCv2 criteria with intra‐arterial… compared with no otoprotective intervention (low certainty).

1 finding from 1 review

Amifostine vs no otoprotective intervention

Ototoxicity according to NCI CTC v2 criteria with intravenous platinum (combined asymptomatic and symptomatic disease) Objective and subjective audiometric evaluations were performed, no further information provided · children with cancer treated with platinum‐based therapy

Amifostine showed no clear difference in ototoxicity according to NCICTCv2 criteria with intravenous platinum… compared with no otoprotective intervention (low certainty).

1 finding from 1 review

Dialectic behaviour therapy with case management vs a health promotion scheme

Number not using methamphetamine at 6 months · summary findings of female review

It is very uncertain whether dialectic behaviour therapy with case management changes number not using methamphetamine at 6 months compared with a health promotion scheme (very low certainty).

1 finding from 1 review