Cochrane · systematic review · CD006085
Antiamoebic drugs for treating amoebic colitis
Gonzales, MLM, Dans, LF, Sio‐Aguilar, J · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 33.3%Low 3 · 50%Moderate 1 · 16.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table 1
Population: adults and children with amoebic colitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Clinical failure | RR 0.17 [0.02, 1.3] | 2 studies · 285 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Parasitological failure Method: stool microscopy demonstrating E histolytica cysts or trophozoites | RR 1.01 [0.58, 1.74] | 2 studies · 285 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Adverse events | RR 0.65 [0.46, 0.92] | 8 studies · 477 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Summary of findings table 2
Population: adults and children with amoebic colitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Clinical failure 1 to 14 days after end of treatment | RR 0.33 [0.11, 0.98] | 3 studies · 1025 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Parasitological failure 1 to 14 days after end of treatment Method: stool microscopy demonstrating E histolytica cysts or trophozoites | RR 0.36 [0.15, 0.86] | 3 studies · 720 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Adverse events | no estimate extracted | 3 studies · 1025 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |