Cochrane · systematic review · CD011400

Food fortification with multiple micronutrients: impact on health outcomes in general population

Das, JK, Salam, RA, Mahmood, SB, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Public HealthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 0 · 0%Very low 2 · 33.3%Low 3 · 50%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: General population
3 questions
OutcomeEffectEvidenceStatus / GRADE
Anaemia Defined as haemoglobin (Hb) concentration < 11 g/dL Measured at after 6 months and 6 ‐ 12 months of intervention
RR 0.68 [0.56, 0.84]11 studies · 3746 participantsLow
Downgraded: risk of bias, inconsistency
Micronutrient deficiencies
RR 0.44 [0.32, 0.6]11 studies · 3289 participantsLow
Downgraded: risk of bias, inconsistency
Anthropometric
no estimate extracted8 studies · 2889 participantsLow
Downgraded: risk of bias, imprecision

Comparison

Population: General population
3 questions
OutcomeEffectEvidenceStatus / GRADE
Anaemia Anaemia was defined as a haemoglobin (Hb) concentration < 13 g/dL for boys and < 12 g/dL for girls Measured after 9 months of intervention
RR 0.86 [0.37, 2.01]1 study · 88 participantsVery low
Downgraded: risk of bias, imprecision
Micronutrient deficiencies
RR 0.98 [0.82, 1.17]1 study · 88 participantsVery low
Downgraded: risk of bias, imprecision
Anthropometric outcomes
no estimate extractedNRNo studies