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Evidence found and GRADE certainty

3,288 questions · 3,354 findings · 516 reviews · Headline outcomes only

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No studies found 720 · 21.5%GRADE not reported 164 · 4.9%Very low 950 · 28.3%Low 932 · 27.8%Moderate 434 · 12.9%High 154 · 4.6%

Beta‐blockers vs control—non‐cardiac surgery

All supraventricular arrhythmias—non‐cardiac surgery ECG · patients with conditions requiring non‐cardiac surgery

Beta‐blocker leads to lower all supraventricular arrhythmias—non‐cardiac surgery ECG compared with control—non‐cardiac surgery (high certainty).

1 finding from 1 review

Beta‐blockers vs control—cardiac surgery

Ventricular arrhythmias—cardiac surgery ECG · patients with coronary heart disease and/or valvular heart disease

Beta‐blocker probably leads to lower ventricular arrhythmias—cardiac surgery ECG compared with control—cardiac surgery (moderate certainty).

1 finding from 1 review

Beta‐blockers vs control—cardiac surgery

All supraventricular arrhythmias—cardiac surgery ECG · patients with coronary heart disease and/or valvular heart disease

Beta‐blocker leads to lower all supraventricular arrhythmias—cardiac surgery ECG compared with control—cardiac surgery (high certainty).

1 finding from 1 review

Desipramine (antidepressant) vs placebo

ADHD symptom‐related behavior Measured by standardized rating scales: Child Behaviour Checklist, Gordon Diagnostic System, Clinical Evaluation of Language Function, Matching Familial Figures Test, Porteus Maze Test, Restricted Academic Test, ADHD ... · children with ADHD and comorbid tic disorders
1 finding from 1 review

tDCS vs sham

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with chronic pain

It is very uncertain whether transcranial direct current stimulation (tDCS) changes pain intensity (0 to < 1 week postintervention) measured using… compared with sham (very low certainty).

1 finding from 1 review

Higher dose vitamin K vs lower dose vitamin K

Intraventricular hemorrhage > Grade II: 0.2 mg IM versus 0.5 mg IM · preterm infants

Higher dose vitamin K showed no clear difference in intraventricular hemorrhage > Grade II: 0.2 mg IM versus 0.5 mg IM compared with lower dose vitamin K (low certainty).

1 finding from 1 review

Intramuscular vitamin K vs intravenous vitamin K

Intraventricular hemorrhage > Grade II: 0.2 mg IV versus 0.2 mg IM · preterm infants

Intramuscular vitamin K showed no clear difference in intraventricular hemorrhage > Grade II: 0.2 mg IV versus 0.2 mg IM compared with intravenous vitamin K (low certainty).

1 finding from 1 review

Intramuscular vitamin K vs intravenous vitamin K

Intraventricular hemorrhage > Grade II: 0.2 mg IV versus 0.5 mg IM · preterm infants

Intramuscular vitamin K showed no clear difference in intraventricular hemorrhage > Grade II: 0.2 mg IV versus 0.5 mg IM compared with intravenous vitamin K (low certainty).

1 finding from 1 review

Intervention not reported

Adverse effects during treatment Intervention: Hyperbaric chamber/ 160 millibars versus supplementary oxygen · people suffering from high altitude illness
1 finding from 1 review

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Severe intraventricular haemorrhage · preterm infants

Lower showed no clear difference in severe intraventricular haemorrhage (grade 3 or 4) compared with higher oxygen concentrations titrated to target oxygen saturations… (low certainty).

1 finding from 1 review

Absorbable vs non‐absorbable sutures

Postoperative pain: early pain (10 days postoperatively) VAS 0 to 10 Verbal reporting scale No pain‐mild pain‐moderate pain‐severe pain (converted to numerical scale (0 to 3, 3 to 6, 6 to 10)
2 findings from 1 review