Cochrane · systematic review · CD011167
Antibiotics for treating gonorrhoea in pregnancy
Comunián‐Carrasco, G, Peña‐Martí, GE, Martí‐Carvajal, AJ · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 7 · 70%Very low 3 · 30%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Intramuscular ceftriaxone compared with oral amoxicillin plus oral probenecid for treating gonorrhoea in pregnancy
Population: pregnant women with gonorrhoea infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Cure of gonococcal infection (microbiological culture) Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid | RR 1.07 [0.98, 1.16] | 1 study · 168 participants | Very low Downgraded: risk of bias, imprecision |
Incidence of obstetric complications Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid | no estimate extracted | 1 study · 168 participants | Ungraded |
Incidence of disseminated gonococcal infection Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid | no estimate extracted | 1 study · 168 participants | Ungraded |
Neonatorum ophthalmia Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid | no estimate extracted | 1 study · 168 participants | Ungraded |
Adverse events including treatment‐related adverse events Intramuscular ceftriaxone vs oral amoxicillin plus oral probenecid | RR 0.33 [0.01, 8.07] | 1 study · 168 participants | Very low Downgraded: risk of bias, imprecision |
Intramuscular ceftriaxone compared with oral cefixime for treating gonorrhoea in pregnancy
Population: pregnant women with gonorrhoea infection
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Cure of gonococcal infection (microbiological culture) Intramuscular ceftriaxone vs oral cefixime | RR 0.99 [0.91, 1.08] | 1 study · 95 participants | Very low Downgraded: risk of bias, imprecision |
Incidence of obstetric complications Intramuscular ceftriaxone vs oral cefixime | no estimate extracted | 1 study · 95 participants | Ungraded |
Incidence of disseminated gonococcal infection Intramuscular ceftriaxone vs oral cefixime | no estimate extracted | 1 study · 95 participants | Ungraded |
Neonatorum ophthalmia Intramuscular ceftriaxone vs oral cefixime | no estimate extracted | 1 study · 95 participants | Ungraded |
Adverse events including treatment‐related adverse events Intramuscular ceftriaxone vs oral cefixime | no estimate extracted | 1 study · 95 participants | Ungraded |