Findings

What do systematic reviews say?

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

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No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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Combined steroid and antibiotic therapy vs antibiotics alone

Costs · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Non‐serious adverse events for all placebos compared with wait‐list or no treatment (Spontaneous reporting of dichotomous outcomes) (Post‐treatment) · patients with mental health disorders

It is very uncertain whether the intervention changes non‐serious adverse events for all placebos compared with wait‐list… (very low certainty).

1 finding from 1 review

Control interventions in randomised trials among people with mental health disorders 2022 · Cochrane Headline outcomes only
RD 0.03
14 studies · 590 participants
Very low

Intervention not reported

Serious adverse events for all placebos · patients with mental health disorders

The review found no eligible studies for this question.

1 finding from 1 review

Control interventions in randomised trials among people with mental health disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Non‐serious adverse events for all placebos · patients with mental health disorders

The review found no eligible studies for this question.

1 finding from 1 review

Control interventions in randomised trials among people with mental health disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Serious adverse events for all placebos compared with wait‐list or no treatment (Spontaneous reporting of dichotomous outcomes) (Post‐treatment) · patients with mental health disorders

It is very uncertain whether the intervention changes serious adverse events for all placebos compared with wait‐list or… (very low certainty).

1 finding from 1 review

Control interventions in randomised trials among people with mental health disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 517 participants
Very low

Intervention not reported

Further surgical or laser interventions · adults with PACS or PAC, and previous PI

The review found no eligible studies for this question.

1 finding from 1 review

Laser peripheral iridoplasty for chronic angle closure 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Further surgical or laser interventions · adults with PAC or PACG, and previous PI

1 finding from 1 review

Laser peripheral iridoplasty for chronic angle closure 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Low

Intervention not reported

Further surgical or laser interventions · adults with PACS, PAC or PACG

1 finding from 1 review

Laser peripheral iridoplasty for chronic angle closure 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 126 participants
Low

Organisation and delivery vs usual care

Comfort in dying · advanced dementia

1 finding from 1 review

Palliative care interventions in advanced dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 335 participants
Very low

Advance care planning vs usual care

Comfort in dying ‐ not measured · advanced dementia

The review found no eligible studies for this question.

1 finding from 1 review

Palliative care interventions in advanced dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Interventions · people with nonalcohol‐related fatty liver disease (NAFLD)

The review found no eligible studies for this question.

1 finding from 1 review

Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Interventions · people with non‐alcohol‐related fatty liver disease (NAFLD)

The review found no eligible studies for this question.

1 finding from 1 review

Nutritional supplementation for nonalcohol‐related fatty liver disease: a network meta‐analysis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intravenous ketorolac vs NSAIDs

Number of women requiring rescue medication · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries

It is very uncertain whether intravenous ketorolac changes number of participants using rescue medication over 4 or 6 hours… compared with another NSAID (very low certainty).

1 finding from 1 review

Single‐dose intravenous ketorolac for acute postoperative pain in adults 2021 · Cochrane Headline outcomes only
RR 0.9 [0.58, 1.4]
3 studies · 260 participants
Very low

Intravenous ketorolac vs placebo

Use of rescue medication · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries

It is very uncertain whether intravenous ketorolac changes number of participants using rescue medication over 4 or 6 hours… compared with placebo (very low certainty).

1 finding from 1 review

Single‐dose intravenous ketorolac for acute postoperative pain in adults 2021 · Cochrane Headline outcomes only
RR 0.6 [0.36, 1]
5 studies · 417 participants
Very low

Oral antibiotics vs placebo

Economic costs and benefits of different interventions · adult participants with chronic blepharitis

The review found no eligible studies for this question.

1 finding from 1 review

Oral antibiotics for chronic blepharitis 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Angioplasty vs primary stenting

Reintervention · patients with symptomatic Iliac artery lesions

Angioplasty showed no clear difference in reinterventions (six to eight years) compared with primary stenting (low certainty).

1 finding from 1 review

Angioplasty versus stenting for iliac artery lesions 2020 · Cochrane Headline outcomes only
OR 1.22 [0.67, 2.23]
1 study · 279 participants
Low

Educational intervention vs control

1.4 Withdrawal ‐ NO META‐ANALYSIS PERFORMED · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1745 participants
GRADE not reported

Educational intervention vs control

1.5 ESS ‐ Comparison of values at endpoint‐ NO META‐ANALYSIS PERFORMED · adults with obstructive sleep apnoea

1 finding from 1 review

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines… 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 355 participants
GRADE not reported

Intervention not reported

Effects on adherence (behavioural interventions) · adults and children with epilepsy

1 finding from 1 review

Strategies for improving adherence to antiepileptic drug treatment in people with epilepsy 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 391 participants
Moderate

Intervention not reported

Effects on adherence (educational interventions) · adults and children with epilepsy

1 finding from 1 review

Strategies for improving adherence to antiepileptic drug treatment in people with epilepsy 2020 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 1938 participants
Moderate