Cochrane · systematic review · CD013156

Lifestyle modifications for nonalcohol‐related fatty liver disease: a network meta‐analysis

Buzzetti, E, Linden, A, Best, LMJ, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
13
No studies
2
Included studies
NR
No studies 2 · 13.3%Ungraded 0 · 0%Very low 12 · 80%Low 1 · 6.7%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Lifestyle modifications for nonalcohol‐related fatty liver disease

Population: people with nonalcohol‐related fatty liver disease (NAFLD)
15 questions
OutcomeEffectEvidenceStatus / GRADE
Interventions
no estimate extractedNRNo studies
No active intervention
no estimate extractedNRNo studies
Aerobic exercise(2 trials; 252 participants)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision
Dietary advice(1 trial; 28 participants)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision
Dietary advice plus exercise advice(1 trial; 265 participants) (another trial 25 participants had zero events in both groups)
HR 0.63NRVery low
Downgraded: risk of bias, imprecision
Mediterranean diet(1 trial; 98 participants)
no estimate extractedNRLow
Downgraded: risk of bias, imprecision
Aerobic exercise plus calorie‐restricted diet(1 trial; 100 participants)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision
Aerobic exercise plus dietary advice(1 trial; 154 participants)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision
Resistance exercise(1 trial; 45 participants)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision
Calorie restricted diet(1 trial; 43 participants)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision
Aerobic exercise(1 trial; 60 participants)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision
Dietary advice plus exercise advice(1 trial; 22 participants)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision
Resistance exercise(1 trial; 62 participants)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision
Aerobic exercise(1 trial; 220 participants)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision
Dietary advice plus exercise advice(2 trials; 287 participants)
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision