Pulmonary air leak defined as pneumothorax · preterm infants
Prophylactic or very early CPAP showed no clear difference in pulmonary air leak defined as pneumothorax compared with supportive care (low certainty).
1 finding from 1 review
Intraventricular haemorrhage, Papile grade 3/4 · preterm infants
Prophylactic or very early CPAP showed no clear difference in intraventricular haemorrhage grade 3 or 4 compared with supportive care (low certainty).
1 finding from 1 review
Neurodevelopmental disability · preterm infants
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Bleeding: Numbers of patients with at least one significant bleeding event · People with a haematological disorder
It is very uncertain whether prophylactic platelet transfusion changes number of participants with a significant bleeding event compared with platelet‐poor plasma (very low certainty).
1 finding from 1 review
Mortality: secondary to bleeding · People with a haematological disorder
It is very uncertain whether prophylactic platelet transfusion changes mortality: secondary to bleeding compared with platelet‐poor plasma (very low certainty).
1 finding from 1 review
Number of platelet transfusions per participant up to 30 days from study entry · People with a haematological disorder
1 finding from 1 review
FEV1 % predicted · children with cystic fibrosis
1 finding from 1 review
Number of people with one or more isolates of S aureus (sensitive strains) · children with cystic fibrosis
Summary of findings ‐ Prophylactic may leads to lower number of people with one or more isolates of S aureus (sensitive… compared with 'as required' anti‐staphylococcal antibiotics (low certainty).
1 finding from 1 review
Number of people with one or more isolates of P aeruginosa · children with cystic fibrosis
Summary of findings ‐ Prophylactic showed no clear difference in number of people with one or more isolates of P aeruginosa compared with 'as required' anti‐staphylococcal antibiotics (low certainty).
1 finding from 1 review
Need for additional antibiotic therapy · children with cystic fibrosis
Summary of findings ‐ Prophylactic showed no clear difference in number of people needing additional antibiotics compared with 'as required' anti‐staphylococcal antibiotics (low certainty).
1 finding from 1 review
Weight (z score) · children with cystic fibrosis
1 finding from 1 review
Acquisition of multiply‐resistant S aureus · children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events of treatment · children with cystic fibrosis
1 finding from 1 review
Mortality ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease
1 finding from 1 review
Quality of life · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease
It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes adverse effects ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).
1 finding from 1 review
Clinical recurrence (until week 102) · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease
It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes clinical recurrence (until week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).
1 finding from 1 review
Endoscopic recurrence · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease
It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes endoscopic recurrence (at week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).
1 finding from 1 review
Surgical recurrence ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease
It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes surgical recurrence ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).
1 finding from 1 review
RR 0.79 [0.38, 1.62]
133 participants
Very low
Occurrence of new cases of colic Measured by: Wessel/Rome III Criteria · infants without colic
Prophylactic probiotics showed no clear difference in occurrence of new cases of colic Measured by: Wessel/Rome III Criteria compared with placebo (low certainty).
1 finding from 1 review