Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics: Need for additional antibiotic therapy
Summary of findings ‐ Prophylactic showed no clear difference in number of people needing additional antibiotics compared with 'as required' anti‐staphylococcal antibiotics (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics Number of people needing additional antibiotics · children with cystic fibrosis Summary of findings ‐ Prophylactic showed no clear difference in number of people needing additional antibiotics compared with 'as required' anti‐staphylococcal antibiotics (low certainty). Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis (2020) · Cochrane Headline outcomes only | OR 0.18 [0.01, 3.6] | 1 study · 119 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis 2020 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.