Cochrane · systematic review · CD012473
Probiotics to prevent infantile colic
Ong, TG, Gordon, M, Banks, SSC, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Developmental, Psychosocial and Learning ProblemsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Prophylactic probiotics compared to placebo for the prevention of infantile colic
Population: infants without colic
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Occurrence of new cases of colic Measured by: Wessel/Rome III Criteria Prophylactic probiotics vs placebo | RR 0.46 [0.18, 1.19] | 3 studies · 1148 participants | Low Downgraded: imprecision, inconsistency |
Adverse effects Measured by: reporting Prophylactic probiotics vs placebo | RR 1.02 [0.14, 7.21] | 6 studies · 1851 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Duration of crying Measured in: minutes per day Prophylactic probiotics vs placebo | no estimate extracted | 3 studies · 707 participants | Low Downgraded: imprecision, inconsistency |