Question · asked by 1 review

Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics: Number of people with one or more isolates of S aureus (sensitive strains)

Summary of findings ‐ Prophylactic may leads to lower number of people with one or more isolates of S aureus (sensitive… compared with 'as required' anti‐staphylococcal antibiotics (low certainty).

What each review found

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FindingEffectStudiesGRADE certainty
Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics
Number of people with one or more isolates of S aureus (sensitive strains) · children with cystic fibrosis
Summary of findings ‐ Prophylactic may leads to lower number of people with one or more isolates of S aureus (sensitive… compared with 'as required' anti‐staphylococcal antibiotics (low certainty).
Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis (2020) · Cochrane Headline outcomes only
OR 0.21 [0.13, 0.35]3 studies · 315 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.