Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery: Endoscopic recurrence
It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes endoscopic recurrence (at week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery Endoscopic recurrence (at week 102) · Adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease. It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes endoscopic recurrence (at week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty). Colonoscopy‐guided therapy for the prevention of post‐operative recurrence of Crohn’s disease (2020) · Cochrane Headline outcomes only | RR 1.16 [0.73, 1.84] | 1 study · 63 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Colonoscopy‐guided therapy for the prevention of post‐operative recurrence of Crohn’s disease 2020 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.