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Evidence found and GRADE certainty

4,667 questions · 21,760 findings · 2,177 reviews

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No studies found 4,173 · 19.2%GRADE not reported 2,300 · 10.6%Very low 5,276 · 24.2%Low 5,764 · 26.5%Moderate 3,298 · 15.2%High 949 · 4.4%

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NIPPV vs NCPAP

Respiratory failure post extubation · preterm neonates after extubation

Nasal intermittent positive pressure ventilation (NIPPV) probably leads to lower respiratory failure postextubation compared with nasal continuous positive airway pressure (NCPAP) (moderate certainty).

1 finding from 1 review

NIPPV vs NCPAP

Gastrointestinal perforation · preterm neonates after extubation

Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in gastrointestinal perforation compared with nasal continuous positive airway pressure (NCPAP) (low certainty).

1 finding from 1 review

NIPPV vs NCPAP

Necrotising enterocolitis · preterm neonates after extubation

Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in necrotising enterocolitis compared with nasal continuous positive airway pressure (NCPAP) (moderate certainty).

1 finding from 1 review

NIPPV vs NCPAP

Chronic lung disease · preterm neonates after extubation

Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in chronic lung disease (oxygen supplementation at 36 weeks) compared with nasal continuous positive airway pressure (NCPAP) (moderate certainty).

1 finding from 1 review

NIPPV vs NCPAP

Mortality before hospital discharge · preterm neonates after extubation

Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in mortality (defined as death before discharge) compared with nasal continuous positive airway pressure (NCPAP) (low certainty).

1 finding from 1 review

Summary of findings table ‐ Preoperative exercise training vs no exercise

Exercise capacity · people scheduled to undergo lung resection for non‐small cell lung cancer
2 findings from 1 review

Interventions for increasing immunosuppressant medication adherence vs usual care

Proportion of immunosuppressant trough concentration levels at target · solid organ transplant recipients

It is very uncertain whether interventions for increasing immunosuppressant medication adherence changes proportion of immunosuppressant trough concentration levels at target compared with standard care (very low certainty).

1 finding from 1 review

High-dose vitamin D3 supplementation during pregnancy (2400 IU/day from pregnancy week 24 to 1 week postpartum, in addition to the recommended 400 IU/day) vs Low-dose (standard) vitamin D supplementation as recommended in national pregnancy guidelines

Dental caries · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…

The review found no eligible studies for this question.

2 findings from 1 review

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (maternal outcomes)

Hypertensive disorders of pregnancy · women with gestational diabetes mellitus

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in hypertensive disorders of pregnancy (including pre‐eclampsia,… compared with less‐tight glycaemic targets (maternal outcomes) (low certainty).

1 finding from 1 review

Intervention not reported

Number of people who returned to living at pre‐fracture residence · adults following hip fracture surgery

The intervention showed no clear difference in number of people who returned to living at pre‐fracture residence (low certainty).

1 finding from 1 review