Cochrane · systematic review · CD003212
Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation
Lemyre, B, Deguise, M-O, Benson, P, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 4 · 57.1%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsNasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) to prevent extubation failure
Population: preterm neonates after extubation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Respiratory failure postextubation Nasal intermittent positive pressure ventilation (NIPPV) vs nasal continuous positive airway pressure (NCPAP) | RR 0.75 [0.67, 0.84] | 19 studies · 2738 participants | Moderate Downgraded: risk of bias |
Endotracheal reintubation Nasal intermittent positive pressure ventilation (NIPPV) vs nasal continuous positive airway pressure (NCPAP) | RR 0.78 [0.7, 0.87] | 17 studies · 2608 participants | Moderate Downgraded: risk of bias |
Gastrointestinal perforation Nasal intermittent positive pressure ventilation (NIPPV) vs nasal continuous positive airway pressure (NCPAP) | RR 0.89 [0.58, 1.38] | 8 studies · 1478 participants | Low Downgraded: risk of bias, imprecision |
Necrotising enterocolitis Nasal intermittent positive pressure ventilation (NIPPV) vs nasal continuous positive airway pressure (NCPAP) | RR 0.86 [0.65, 1.15] | 10 studies · 2069 participants | Moderate Downgraded: risk of bias |
Chronic lung disease (oxygen supplementation at 36 weeks) Nasal intermittent positive pressure ventilation (NIPPV) vs nasal continuous positive airway pressure (NCPAP) | RR 0.93 [0.84, 1.05] | 9 studies · 2001 participants | Moderate Downgraded: risk of bias |
Pulmonary air leak Nasal intermittent positive pressure ventilation (NIPPV) vs nasal continuous positive airway pressure (NCPAP) | RR 0.57 [0.37, 0.87] | 13 studies · 2404 participants | Low Downgraded: risk of bias, imprecision |
Mortality (defined as death before discharge) Nasal intermittent positive pressure ventilation (NIPPV) vs nasal continuous positive airway pressure (NCPAP) | RR 0.81 [0.61, 1.07] | 11 studies · 2258 participants | Low Downgraded: risk of bias, imprecision |