Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,479 questions · 1,537 findings · 159 reviews

No studies found 364 · 23.7%GRADE not reported 125 · 8.1%Very low 455 · 29.6%Low 374 · 24.3%Moderate 193 · 12.6%High 26 · 1.7%

Tricyclic antidepressants vs behavioural interventions

Number not achieving 14 consecutive dry nights at the end of treatment ‐ imipramine vs 3 step therapy (reassurance, retention control training + wakening, parental involvement) · children with nocturnal enuresis

Tricyclics may leads to higher number not achieving 14 consecutive dry nights at the end of… compared with behavioural interventions (low certainty).

1 finding from 1 review

Intervention not reported

Family relationship Pre‐intervention and post‐intervention assessment Home visits and training session for family members Patient‐caregiver relationships assessed pre‐intervention and immediately post‐intervention. · caregivers of patients with sickle cell disease
1 finding from 1 review

Intervention not reported

Task‐oriented training · people with multiple sclerosis
1 finding from 1 review