Cochrane · systematic review · CD009956
Exercise therapy for fatigue in multiple sclerosis
Heine, M, van de Port, I, Rietberg, MB, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Multiple Sclerosis and Rare Diseases of the CNSAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
11
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 9.1%Low 4 · 36.4%Moderate 6 · 54.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Overall analysis for fatigue in multiple sclerosis
Population: people with multiple sclerosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fatigue | no estimate extracted | 36 studies · 1603 participants | Moderate |
Exercise versus no‐exercise control | no estimate extracted | 27 studies · 1325 participants | Moderate |
Exercise versus exercise | no estimate extracted | 9 studies · 278 participants | Low |
Per fatigue measure for fatigue in multiple sclerosis
Population: people with multiple sclerosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Modified Fatigue Impact Scale | no estimate extracted | 8 studies · 688 participants | Moderate |
Fatigue Severity Scale | no estimate extracted | 13 studies · 449 participants | Moderate |
Other | no estimate extracted | 5 studies · 167 participants | Low |
Per exercise group for fatigue in multiple sclerosis
Population: people with multiple sclerosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Endurance training | no estimate extracted | 11 studies · 266 participants | Moderate |
Muscle power training | no estimate extracted | 4 studies · 207 participants | Low Downgraded: imprecision |
Task‐oriented training | no estimate extracted | 2 studies · 36 participants | Very low |
Mixed training | no estimate extracted | 6 studies · 495 participants | Moderate |
'Other' training | no estimate extracted | 9 studies · 295 participants | Low |