Cochrane · systematic review · CD011175
Interventions for patients and caregivers to improve knowledge of sickle cell disease and recognition of its related complications
Asnani, MR, Quimby, KR, Bennett, NR, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Cystic Fibrosis and Genetic DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
6
No studies
2
Included studies
NR
No studies 2 · 25%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 25%Moderate 4 · 50%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: patients with sickle cell disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
SCD knowledge:children Pre‐ and post‐knowledge assessment Duration of | no estimate extracted | 4 studies · 160 participants | Moderate Downgraded: risk of bias |
Healthcare utilization clinic visits, emergency room visits and hospital admissions Duration of | no estimate extracted | 2 studies · 176 participants | Moderate Downgraded: risk of bias |
Positive coping Coping attempts and coping strategies Duration of | no estimate extracted | 5 studies · 208 participants | Low Downgraded: risk of bias |
Depression standardised depression scores | no estimate extracted | 3 studies · 135 participants | Moderate Downgraded: risk of bias |
Patient‐reported signs and symptoms/ self‐management | no estimate extracted | NR | No studies |
Comparison
Population: caregivers of patients with sickle cell disease
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
SCD knowledge: caregiver Pre‐ and post‐knowledge assessment Duration of | no estimate extracted | 1 study · 39 participants | Low Downgraded: risk of bias |
Family relationship Pre‐intervention and post‐intervention assessment Home visits and training session for family members Patient‐caregiver relationships assessed pre‐intervention and immediately post‐intervention. | no estimate extracted | 2 studies · 76 participants | Moderate Downgraded: risk of bias |
Caregiver‐reported signs and symptoms Lead to self management | no estimate extracted | NR | No studies |