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Evidence found and GRADE certainty

3,429 questions · 3,558 findings · 436 reviews

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No studies found 660 · 18.5%GRADE not reported 375 · 10.5%Very low 727 · 20.4%Low 887 · 24.9%Moderate 709 · 19.9%High 200 · 5.6%

IMMEDIATE initiation of cART vs DEFERRED initiation of cART

Patient or population: HIV‐positive, treatment‐naive children aged 24 to 59 months (2 to 5 years old)Settings: Thailand and CambodiaIntervention: IMMEDIATE initiation of cARTComparison: DEFERRED initiation of cART · HIV‐positive, treatment‐naive children aged one to 12 years old

The review found no eligible studies for this question.

1 finding from 1 review

Resin composite restorations containing antibacterial agents vs Non-antibacterial containing composite restorations

Postoperative sensitivity, marginal adaptation, anatomic form and other clinical outcomes (USPHS restoration quality; includes tooth vitality and pulpitis) · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition

The review found no eligible studies for this question.

1 finding from 1 review

No dentinal caries removal (caries sealed under a preformed metal crown or restoration without removing dentinal caries) vs Complete caries removal

Signs or symptoms of pulpal disease · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth

No dentinal caries removal (caries sealed under a preformed metal… showed no clear difference in signs or symptoms of pulpal disease compared with complete caries removal (moderate certainty).

1 finding from 1 review

Systems training for emotional predictability and problem solving for borderline personality disorder + individual therapy (STEPPS+IT) vs treatment

Impulsivity · patients with borderline personality disorder

Systems training for emotional predictability and problem solving… showed no clear difference in impulsivityno. of participants scoring above BPDSI‐IV3 impulsivity… compared with treatment (low certainty).

1 finding from 1 review

Early routine ERCP strategy vs early conservative management with or without delayed or selective ERCP strategy

Systemic complications defined by the Atlanta Classification (organ failure including shock, pulmonary insufficiency, renal failure, and gastrointestinal bleeding; disseminated intravascular coagulation or severe metabolic disturbances) · patients with unselected patients with acute gallstone pancreatitis

Early routine ERCP strategy showed no clear difference in systemic complications defined by the Atlanta Classification (organ… compared with early conservative management with or without delayed or selective… (moderate certainty).

1 finding from 1 review

Hypnosis vs No hypnosis (no hypnotic intervention)

Physiological measures during local anaesthesia (pulse rate and oxygen saturation) · Children aged 4 to 13 years with no previous dental experience undergoing restorative treatment with local anaesthesia (Gokli 1994)
1 finding from 1 review
  • Hypnosis for children undergoing dental treatment 2010 · Cochrane All outcomes
    With regard to oxygen saturation and pulse rate, only pulse rate was significantly lower in the hypnosis group (P = 0.005); oxygen saturation did not differ significantly. (Gokli 1994; cross-over, 29 children.)
    1 study · 29 participants
    GRADE not reported

PPI plus usual care vs usual care alone or chronic obstructive pulmonary disease

Exacerbations · patients with chronic obstructive pulmonary disease

PPI plus usual care may leads to lower exacerbation rate (participants with one or more) study duration: 12… compared with usual care alone or chronic obstructive pulmonary disease (low certainty).

1 finding from 1 review