Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Intervention not reported

Proportion of successful procedures at 1 year and up to 5 years after surgery (no exposure/extrusion) · people with anophthalmic sockets

The intervention showed no clear difference in proportion of successful procedures at 1 year and up to 5 years… (low certainty).

1 finding from 1 review

Intensive vs less intensive continuous renal replacement therapy (CRRT)

Mortality: patients with AKI related to cardiac or general surgery · patients with AKI who need CRRT

Intensive leads to lower mortality: patients with AKI related to cardiac or general surgery compared with less intensive continuous renal replacement therapy (CRRT) (high certainty).

1 finding from 1 review

Intensive vs less intensive continuous renal replacement therapy (CRRT)

Mortality: patients with AKI not related to surgery · patients with AKI who need CRRT

Intensive showed no clear difference in mortality: patients with AKI not related to surgery compared with less intensive continuous renal replacement therapy (CRRT) (low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Failure of treatment and adverse effects: long‐term Participants with surgery and symptom recurrence · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes failure of treatment and adverse effects: long‐term Participants… compared with microfracture (very low certainty).

1 finding from 1 review

Intervention not reported

Treatment failure (meniscal surgery) at 5 years5,7 · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)

The intervention showed no clear difference in treatment failure (meniscal surgery) at 5 years5,7 (low certainty).

1 finding from 1 review

Intervention not reported

Minimally invasive step‐up approach: planned surgery vs. continued percutaneous drainage · people with necrotising pancreatitis

It is very uncertain whether the intervention changes minimally invasive step‐up approach: planned surgery vs. continued… (very low certainty).

1 finding from 1 review

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Long‐term mortality (time‐to‐event outcome): chemoradiotherapy versus surgery All‐cause mortality for the duration of · patients with oesophageal cancer

Non‐surgical showed no clear difference in long‐term mortality (time‐to‐event outcome): chemoradiotherapy… compared with surgical treatment of oesophageal cancer (primary outcomes) (low certainty).

2 findings from 1 review

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Long‐term mortality (time‐to‐event outcome): radiotherapy versus surgery All‐cause mortality for the duration of · patients with oesophageal cancer

It is very uncertain whether non‐surgical changes long‐term mortality (time‐to‐event outcome): radiotherapy versus… compared with surgical treatment of oesophageal cancer (primary outcomes) (very low certainty).

1 finding from 1 review

Non‐surgical vs surgical treatment of oesophageal cancer (primary outcomes)

Long‐term mortality (binary outcome) All‐cause mortality for the duration of · patients with oesophageal cancer

Non‐surgical showed no clear difference in long‐term mortality (binary): definitive chemoradiotherapy versus… compared with surgical treatment of oesophageal cancer (primary outcomes) (low certainty).

1 finding from 1 review

Intervention not reported

Postoperative mortality (within 30 days from surgery) · patients with resectable disease

The intervention leads to higher postoperative mortality (within 30 days from surgery) (high certainty).

1 finding from 1 review

Mobile bearing vs fixed bearing prosthesis

Revision surgery · patients with posterior cruciate retaining total knee arthroplasty for postoperative functional status in patients with osteoarthritis and…

Mobile bearing may leads to lower revision surgery compared with fixed bearing prosthesis (low certainty).

1 finding from 1 review

Transmyocardial laser revascularization vs medical treatment

Early postoperative mortality Deaths in the 30 days after surgery · patients with refractory angina

Transmyocardial laser revascularization showed no clear difference in early postoperative mortality Deaths in the 30 days after surgery compared with medical treatment (high certainty).

1 finding from 1 review

Intervention not reported

Although a higher percentage of people in the ATL and aCCT groups fell within Class I (seizure free) and Class II (> 50% reduction in seizures), no significant differences in seizure frequency were noted between the groups at 2 years after surgery... · people with temporal lobe epilepsy and intellectual disabilities
1 finding from 1 review

Gentamicin sponge vs primary closure

Adverse effects ‐ complication rate at 1 week after surgery · participants with hidradenitis suppurativa

Gentamicin sponge showed no clear difference in adverse effects ‐ complication rate at 1 week after surgery compared with primary closure alone (moderate certainty).

1 finding from 1 review