Cochrane · systematic review · CD003712

Transmyocardial laser revascularization versus medical therapy for refractory angina

Briones, E, Lacalle, JR, Marin‐Leon, I, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 2 · 33.3%High 2 · 33.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Transmyocardial laser revascularization compared to medical treatment for refractory angina

Population: patients with refractory angina
6 questions
OutcomeEffectEvidenceStatus / GRADE
Angina reduction Decrease in two angina classes or more
Transmyocardial laser revascularization vs medical treatment
OR 4.63 [3.43, 6.25]7 studies · 1051 participantsLow
Downgraded: risk of bias, inconsistency
Angina reduction ‐ CCS score Decrease in two angina classes or more
Transmyocardial laser revascularization vs medical treatment
OR 3.95 [2.9, 5.39]5 studies · 923 participantsLow
Downgraded: risk of bias, inconsistency
Angina reduction ‐ NYHA scale Decrease in two angina classes or more
Transmyocardial laser revascularization vs medical treatment
OR 68.32 [7.95, 587.38]2 studies · 128 participantsModerate
Downgraded: risk of bias
Overall mortality
Transmyocardial laser revascularization vs medical treatment
OR 1.12 [0.77, 1.63]7 studies · 1053 participantsHigh
Early postoperative mortality Deaths in the 30 days after surgery
Transmyocardial laser revascularization vs medical treatment
OR 1.19 [0.63, 2.24]6 studies · 967 participantsHigh
Exercise tolerance Minutes
Transmyocardial laser revascularization vs medical treatment
no estimate extracted2 studies · 129 participantsModerate
Downgraded: risk of bias