Cochrane · systematic review · CD011166

Surgical versus conservative interventions for treating anterior cruciate ligament injuries

Monk, AP, Davies, LJ, Hopewell, S, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Bone, Joint and Muscle TraumaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 1 · 14.3%Low 5 · 71.4%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Subjective knee score ‐ KOOS‐4 score (mean score of 4 components) at 2 years: score from 0 (extreme symptoms) to 100 (no symptoms)
no estimate extracted1 study · 121 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Serious adverse events (such as donor site morbidity, failure of graft including re‐rupture) at 2 years
no estimate extracted1 study · 121 participantsUngraded
Treatment failure (graft rupture or ACL reconstruction) at 2 years5
RR 0.12 [0.04, 0.34]1 study · 121 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Treatment failure (meniscal surgery) at 5 years5,7
RR 0.88 [0.62, 1.25]1 study · 120 participantsLow
Downgraded: risk of bias, imprecision, indirectness
General health‐related quality of life: SF‐36 physical component score (range 0 to 100; higher score = better health state) at 2 years
no estimate extracted1 study · 121 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Return to activity or level of sport at 2 years
RR 1.22 [0.78, 1.91]1 study · 121 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Osteoarthritis at 5 years
RR 1.8 [0.92, 3.52]1 study · 113 participantsVery low
Downgraded: risk of bias, imprecision, indirectness