Adverse effects (dropouts) · participants of any age with a primary diagnosis of major depressive disorder
Brexpiprazole leads to higher number of dropouts due to adverse effects at 8 weeks compared with antidepressive agents (high certainty).
1 finding from 1 review
Remission · participants of any age with a primary diagnosis of major depressive disorder
Brexpiprazole leads to higher remission rates at 8 weeks compared with antidepressive agents (high certainty).
1 finding from 1 review
Adverse effects: 2. Extrapyramidal ‐ akathisia · participants of any age with a primary diagnosis of major depressive disorder
Brexpiprazole probably leads to higher adverse effects: akathisia (followed up until the end of the longest compared with antidepressive agents (moderate certainty).
1 finding from 1 review
Weight gain · participants of any age with a primary diagnosis of major depressive disorder
Brexpiprazole probably leads to higher adverse effects: weight gain (followed up until the end of the longest compared with antidepressive agents (moderate certainty).
1 finding from 1 review
Positive‐pressure ventilation after institution of treatment · treatment of apnea
It is very uncertain whether doxapram changes 2a. Need for positive pressure ventilation after initiation of… compared with no treatment, placebo, methylxanthine (including theophylline,… (very low certainty).
3 findings from 1 review
Treatment failure · preterm infants receiving nasal CPAP
Bubble may leads to lower treatment failure compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).
1 finding from 1 review
Mortality before hospital discharge · preterm infants receiving nasal CPAP
Bubble showed no clear difference in all‐cause mortality before hospital discharge compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).
1 finding from 1 review
Neurodevelopmental disability · preterm infants receiving nasal CPAP
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pneumothorax · preterm infants receiving nasal CPAP
Bubble showed no clear difference in pneumothorax compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).
1 finding from 1 review
Moderate‐severe nasal injury · preterm infants receiving nasal CPAP
Bubble probably leads to higher moderate‐severe nasal injury compared with ventilator or Infant Flow Driver nasal continuous positive airway… (moderate certainty).
1 finding from 1 review
Bronchopulmonary dysplasia · preterm infants receiving nasal CPAP
Bubble showed no clear difference in bronchopulmonary dysplasia compared with ventilator or Infant Flow Driver nasal continuous positive airway… (low certainty).
1 finding from 1 review
Malaria parasite prevalence · people living in malaria‐endemic areas
Topical repellents may leads to lower malaria prevalence ( compared with placebo or no treatment (low certainty).
1 finding from 1 review
Fever · Residents of nursing homes and other long-term care facilities
Professional oral care led to lower incidence or prevalence of fever compared with usual oral care; GRADE not reported.
1 finding from 1 review
Symptomatic DVT · adults undergoing KA
Low‐molecular‐weight heparin showed no clear difference in symptomatic DVT: assessed by presence of symptoms and confirmed by a… compared with no prophylaxis (low certainty).
1 finding from 1 review
Number of participants who used prescribed antibiotics for acute URTIs · children, adults, and the elderly
Intention‐to‐treat analysis: probiotics probably leads to lower number of participants who used prescribed antibiotics for acute URTIs compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Need for precut sphincterotomy · Patients undergoing diagnostic or therapeutic ERCP
Guidewire‐assisted cannulation probably leads to lower need for precut sphincterotomy compared with contrast‐assisted cannulation (moderate certainty).
1 finding from 1 review
Systolic blood pressure · People who may be at risk for primary hypertension
2 findings from 1 review
Diastolic blood pressure · People who may be at risk for primary hypertension
1 finding from 1 review
Systolic blood pressure. Dose less than 1000 mg a day (range of · People who may be at risk for primary hypertension
1 finding from 1 review
Systolic blood pressure. Dose between 1000 mg a day and less than 1500 mg a day · People who may be at risk for primary hypertension
1 finding from 1 review