Cochrane · systematic review · CD009662

Guidewire‐assisted cannulation of the common bile duct for the prevention of post‐endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis

Tse, F, Liu, J, Yuan, Y, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

Gut2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 2 · 28.6%Moderate 4 · 57.1%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Guidewire‐assisted cannulation compared to contrast‐assisted cannulation for the prevention of post‐ERCP pancreatitis (PEP)

Population: Patients undergoing diagnostic or therapeutic ERCP
7 questions
OutcomeEffectEvidenceStatus / GRADE
Post‐ERCP pancreatitis (PEP)
Guidewire‐assisted cannulation vs contrast‐assisted cannulation
RR 0.51 [0.36, 0.72]15 studies · 4426 participantsModerate
Downgraded: risk of bias
Primary cannulation success
Guidewire‐assisted cannulation vs contrast‐assisted cannulation
RR 1.06 [1.01, 1.12]13 studies · 3962 participantsLow
Downgraded: risk of bias
Overall cannulation success
Guidewire‐assisted cannulation vs contrast‐assisted cannulation
RR 1.01 [1, 1.03]15 studies · 4426 participantsModerate
Downgraded: risk of bias
Need for precut sphincterotomy
Guidewire‐assisted cannulation vs contrast‐assisted cannulation
RR 0.79 [0.64, 0.96]10 studies · 2849 participantsModerate
Downgraded: risk of bias
Post‐sphincterotomy bleeding
Guidewire‐assisted cannulation vs contrast‐assisted cannulation
RR 0.87 [0.49, 1.54]7 studies · 2122 participantsLow
Downgraded: risk of bias
Perforation
Guidewire‐assisted cannulation vs contrast‐assisted cannulation
RR 0.93 [0.11, 8.23]8 studies · 2522 participantsVery low
Downgraded: risk of bias
Mortality
Guidewire‐assisted cannulation vs contrast‐assisted cannulation
no estimate extracted6 studies · 2276 participantsModerate
Downgraded: risk of bias