Cochrane · systematic review · CD015422

Topical repellents for malaria prevention

Gabaldón Figueira, JC, Wagah, MG, Adipo, LB, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 20%Very low 0 · 0%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Topical repellents versus placebo or no treatment in adults and children living in malaria‐endemic areas

Population: adults and children in malaria‐endemic areas
5 questions
OutcomeEffectEvidenceStatus / GRADE
Malaria infection incidence alone(
Topical repellents vs placebo or no treatment
Rate ratio 0.76 [0.56, 1.02]1 study · 12813 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Malaria case incidence alone(
Topical repellents vs placebo or no treatment
Rate ratio 0.66 [0.32, 1.36]48838 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Malaria case and infection incidence together (
Topical repellents vs placebo or no treatment
Rate ratio 0.74 [0.56, 0.98]1 study · 61651 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Adverse events
Topical repellents vs placebo or no treatment
no estimate extracted1 study · 47515 participantsUngraded
Malaria prevalence (
Topical repellents vs placebo or no treatment
Odds ratio 0.81 [0.67, 0.97]1 study · 55366 participantsLow
Downgraded: risk of bias, imprecision, indirectness