Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,018 questions · 3,100 findings · 369 reviews · Headline outcomes only

No studies found 774 · 25%GRADE not reported 108 · 3.5%Very low 727 · 23.5%Low 840 · 27.1%Moderate 474 · 15.3%High 177 · 5.7%

Continuous positive airway pressure (CPAP) vs phosphodiesterase type 5 inhibitors

Minor adverse events · erectile dysfunction in men with obstructive sleep apnoea

It is very uncertain whether continuous positive airway pressure (CPAP) changes minor adverse events compared with phosphodiesterase type 5 inhibitors (very low certainty).

1 finding from 1 review

Vitamin K antagonists vs low molecular weight heparin

Minor bleeding · ambulatory patients with multiple myeloma receiving immunomodulatory agents

It is very uncertain whether vitamin K antagonist (VKA) changes minor bleeding compared with low molecular weight heparin (LMWH) (very low certainty).

1 finding from 1 review

Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics

Number of people with one or more isolates of P aeruginosa · children with cystic fibrosis

Summary of findings ‐ Prophylactic showed no clear difference in number of people with one or more isolates of P aeruginosa compared with 'as required' anti‐staphylococcal antibiotics (low certainty).

1 finding from 1 review

Vitamin A vs placebo

Adverse events: minor gastrointestinal symptoms · healthy people and healthy male physicians

Vitamin A leads to higher adverse events: minor gastrointestinal symptoms compared with placebo (high certainty).

1 finding from 1 review

Intervention not reported

Retinopathy of prematurity (stage ≥ 3) · preterm infants with low birth weight

The intervention showed no clear difference in retinopathy of prematurity (stage ≥ 3) (high certainty).

1 finding from 1 review

Intervention not reported

Retinopathy of prematurity (all stages or stage not reported) during initial hospital stay · preterm infants with low birth weight

It is very uncertain whether the intervention changes retinopathy of prematurity (all stages or stage not reported) during… (very low certainty).

1 finding from 1 review

Intervention not reported

Retinopathy of prematurity (stage ≥ 3) during initial hospital stay · preterm infants with low birth weight

It is very uncertain whether the intervention changes retinopathy of prematurity (stage ≥ 3) during initial hospital stay (very low certainty).

1 finding from 1 review