Cochrane · systematic review · CD013504
Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias
Bawazeer, GA, Alkofide, HA, Alsharafi, AA, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 3 · 42.9%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias
Population: adults with arrhythmias undergoing catheter ablation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcomes and Interrupted vs uninterrupted anticoagulation therapy | no estimate extracted | NR | No studies |
Thromboembolic events Interrupted vs uninterrupted anticoagulation therapy | RR 1.76 [0.33, 9.46] | 6 studies · 3468 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Major bleeding Interrupted vs uninterrupted anticoagulation therapy | RR 1.1 [0.59, 2.05] | 10 studies · 4584 participants | Low Downgraded: risk of bias, imprecision |
Composite endpoint of thromboembolic events (stroke or systemic embolism), major bleeding events, and all‐cause mortality Interrupted vs uninterrupted anticoagulation therapy | RR 0.23 [0.07, 0.81] | 1 study · 442 participants | Low Downgraded: risk of bias, imprecision |
Minor bleeding Interrupted vs uninterrupted anticoagulation therapy | RR 1.01 [0.46, 2.22] | 9 studies · 3843 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
All‐cause mortality Interrupted vs uninterrupted anticoagulation therapy | RR 0.34 [0.01, 8.21] | 1 study · 442 participants | Low Downgraded: risk of bias, imprecision |
Asymptomatic thromboembolic events Interrupted vs uninterrupted anticoagulation therapy | RR 1.45 [0.85, 2.47] | 6 studies · 1268 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |