Mean birthweight · Pregnant women who smoke
Nicotine replacement therapy showed no clear difference in mean birthweight (g) compared with control (low certainty).
1 finding from 1 review
Miscarriage and spontaneous abortion · Pregnant women who smoke
Nicotine replacement therapy showed no clear difference in miscarriage and spontaneous abortion compared with control (low certainty).
1 finding from 1 review
Blood lossTime point: mean 48 hours, range 1 to 13 days. Higher blood loss indicates a worse outcome. · people undergoing total knee replacement
1 finding from 1 review
Pain at post‐operative day 2Scale from 0 (best) to 10 (worst). · people undergoing total knee replacement
1 finding from 1 review
Transfusion rate · people undergoing total knee replacement
It is very uncertain whether any cold therapy changes transfusion rate compared with no cold therapy following total knee replacement (very low certainty).
1 finding from 1 review
Range of motion at discharge Scale from: 0 to 125. · people undergoing total knee replacement
1 finding from 1 review
Function Standardised scale with positive score indicating a better outcome. Scale from 0 (worst) to 100 (best). · people undergoing total knee replacement
1 finding from 1 review
Adverse events Adverse events included discomfort, local skin reactions, superficial infections, cold induced injuries and thrombolytic events · people undergoing total knee replacement
It is very uncertain whether any cold therapy changes total adverse eventsAdverse events included discomfort, local skin… compared with no cold therapy following total knee replacement (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people undergoing total knee replacement
It is very uncertain whether any cold therapy changes withdrawals due to adverse events compared with no cold therapy following total knee replacement (very low certainty).
1 finding from 1 review
Smoking cessation · people who smoke
Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in smoking cessation (at least six months of compared with NRT alone (low certainty).
1 finding from 1 review
Serious adverse events · people who smoke
Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in serious adverse events compared with NRT alone (low certainty).
1 finding from 1 review
Dropouts due to treatment · people who smoke
Bupropion plus nicotine replacement therapy (NRT) showed no clear difference in dropouts due to treatment compared with NRT alone (low certainty).
1 finding from 1 review
Change in weight (kg) · People who have quit smoking
Nicotine replacement therapy for smoking cessation showed no clear difference in mean weight change (kg) at end of treatment compared with placebo (moderate certainty).
3 findings from 1 review
MD 0.52
21 studies · 2784 participants
Moderate
MD 0.08
11 studies · 1021 participants
Moderate
MD 0.37
17 studies · 1463 participants
Moderate
Prevalence of Wolbachia‐carrying mosquitoes (for population replacement strategy) · children and adults at risk of dengue infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Renal replacement therapy · hospitalized, mechanically ventilated adults with confirmed SARS‐CoV‐2 infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
New initiation of renal replacement therapy – at longest available · people with AHF
Ultrafiltration (UF) showed no clear difference in new initiation of renal replacement therapy – at longest available compared with usual care (UC) (low certainty).
1 finding from 1 review
Intervention not reported
Knee surgery (replacement or osteotomy)Last · people with degenerative knee disease (osteoarthritis including degenerative meniscal tears)
The intervention showed no clear difference in knee surgery (replacement or osteotomy)Last (low certainty).
1 finding from 1 review
Clinical progression: need for NIV, IMV, ECMO, or renal replacement therapy at day 5 (group 5, 6 or 7) · hospitalised individuals with COVID‐19 (moderate to severe disease)
It is very uncertain whether bamlanivimab changes clinical progression: need for NIV, IMV, ECMO, or renal replacement… compared with placebo (very low certainty).
1 finding from 1 review
Physical health: Reduction of bleedings, factor replacement, pain · adults and children with hemophilia
1 finding from 1 review
no estimate extracted
1 study · 7 participants
Very low
Intervention not reported
Aldosterone antagonists plus loop diuretics plus systemic vasoconstrictors plus paracentesis plus fluid replacement (No direct RCT) · people with liver cirrhosis and ascites
It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus systemic… (very low certainty).
1 finding from 1 review
HR 1.11 [0.02, 39.77]
Studies not reported
Very low