evidence/gaps
Cochrane · systematic review · CD015532

Early versus late tracheostomy in critically ill COVID‐19 patients

Szafran, A, Dahms, K, Ansems, K, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

HaematologyAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
5
No studies
4
Included studies
NR
No studies 4 · 44.4%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 55.6%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Early versus late tracheostomy in critically ill COVID‐19 patients

Population: hospitalized, mechanically ventilated adults with confirmed SARS‐CoV‐2 infection
9 questions
OutcomeEffectEvidenceStatus / GRADE
Evidence from RCTs
Early vs late tracheostomy
no estimate extractedNRNo studies
Mortality
Early vs late tracheostomy
no estimate extractedNRNo studies
Overall mortality
Early vs late tracheostomy
RR 0.82 [0.52, 1.29]1 study · 150 participantsLow
Downgraded: imprecision
Duration to liberation from mechanical ventilation
Early vs late tracheostomy
no estimate extracted1 study · 150 participantsLow
Downgraded: imprecision
Adverse events (any grade)
Early vs late tracheostomy
RR 0.94 [0.79, 1.13]1 study · 150 participantsLow
Downgraded: imprecision
Ventilator‐associated pneumonia
Early vs late tracheostomy
RR 1.08 [0.23, 5.2]1 study · 150 participantsLow
Downgraded: imprecision
Need for renal replacement therapy
Early vs late tracheostomy
no estimate extractedNRNo studies
ICU length of stay
Early vs late tracheostomy
no estimate extracted1 study · 150 participantsLow
Downgraded: imprecision
Evidence from NRSIs
Early vs late tracheostomy
no estimate extractedNRNo studies