Mean number of antiglaucoma medications at 1‐year · People with glaucoma
Aqueous shunts may leads to higher mean number of antiglaucoma medications at 1‐year compared with trabeculectomy (low certainty).
1 finding from 1 review
Adverse effects: ocular allergy to the study medication requiring discontinuation up to 4 years' · people with open‐angle glaucoma
It is very uncertain whether neuroprotection changes adverse effects: ocular allergy to the study medication requiring… compared with control (very low certainty).
1 finding from 1 review
Intervention not reported
Adverse effects of medication, at any time during treatment · children with blepharokeratoconjunctivitis
1 finding from 1 review
Mean change in medications Measured by number of bottles · patients with eyes with cataract and glaucoma
Combined surgery showed no clear difference in mean change in medications Measured by number of bottles compared with phacoemulsification alone (low certainty).
1 finding from 1 review
Proportion using one or more medications at one year after surgery Number of participants · patients with eyes with cataract and glaucoma
Combined surgery may leads to lower proportion using one or more medications at one year after surgery… compared with phacoemulsification alone (low certainty).
1 finding from 1 review
Failure at 12 months Need for repeat surgery or uncontrolled IOP (usually more than 22 mm Hg) despite additional topical or systemic medications · participants with glaucoma surgery
Intraoperative 5‐Fluorouracil leads to lower failure at 12 months Need for repeat surgery or uncontrolled IOP… compared with placebo or control (high certainty).
1 finding from 1 review
Combined symptom‐medication scores Symptom scores · patients with allergic conjunctivitis
1 finding from 1 review
Failure to control IOP (as defined by study investigators) · people with open‐angle glaucoma
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Failure to stabilise visual field progression (as defined by study investigators) · people with open‐angle glaucoma
Laser trabeculoplasty showed no clear difference in failure to stabilise visual field progression (as defined by study… compared with medication (moderate certainty).
1 finding from 1 review
RR 0.7 [0.42, 1.16]
Studies not reported
Moderate
Failure to stabilise optic neuropathy progression (as defined by study investigators) · people with open‐angle glaucoma
It is very uncertain whether laser trabeculoplasty changes failure to stabilise optic neuropathy progression (as defined by… compared with medication (very low certainty).
1 finding from 1 review
RR 0.73 [0.44, 1.2]
Studies not reported
Very low
Quality of life measures · people with open‐angle glaucoma
Laser trabeculoplasty showed no clear difference in quality of life measures compared with medication (moderate certainty).
1 finding from 1 review
MD 0.28
Studies not reported
Moderate
Adverse effects:PAS formation · people with open‐angle glaucoma
Laser trabeculoplasty may leads to higher adverse effects:PAS formation compared with medication (low certainty).
1 finding from 1 review
RR 11.74 [5.94, 23.22]
Studies not reported
Low
Adverse effects: IOP spikes · people with open‐angle glaucoma
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Costs · people with open‐angle glaucoma
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Mean change in number of IOP‐lowering drops from baseline · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review
Proportion of participants who required further glaucoma surgery, including laser · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review
Glaucoma progression at 12 months, measured by additional visual field defects · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mean change in health‐related quality of life · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intraoperative and postoperative complications · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review
Mean change in unmedicated IOP (after washout) measured using Goldmann applanation tonometry medium‐term · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review