Cochrane · systematic review · CD003919
Laser trabeculoplasty for open‐angle glaucoma and ocular hypertension
Rolim-de-Moura, CR, Paranhos Jr, A, Loutfi, M, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
13
current version
GRADE rated
11
No studies
2
Included studies
NR
No studies 2 · 15.4%Ungraded 0 · 0%Very low 3 · 23.1%Low 4 · 30.8%Moderate 4 · 30.8%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Laser trabeculoplasty versus medication
Population: people with open‐angle glaucoma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Failure to control IOP (as defined by study investigators) Laser trabeculoplasty vs medication | no estimate extracted | NR | Low Downgraded: risk of bias |
Failure to stabilise visual field progression (as defined by study investigators) Laser trabeculoplasty vs medication | RR 0.7 [0.42, 1.16] | NR | Moderate Downgraded: risk of bias |
Failure to stabilise optic neuropathy progression (as defined by study investigators) Laser trabeculoplasty vs medication | RR 0.73 [0.44, 1.2] | NR | Very low Downgraded: risk of bias |
Quality of life measures Laser trabeculoplasty vs medication | MD 0.28 | NR | Moderate Downgraded: risk of bias |
Adverse effects:PAS formation Laser trabeculoplasty vs medication | RR 11.74 [5.94, 23.22] | NR | Low Downgraded: risk of bias |
Adverse effects: IOP spikes Laser trabeculoplasty vs medication | no estimate extracted | NR | Moderate Downgraded: risk of bias |
Costs Laser trabeculoplasty vs medication | no estimate extracted | NR | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Laser trabeculoplasty versus trabeculectomy
Population: people with open‐angle glaucoma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Failure to control IOP (as defined by study investigators) Laser trabeculoplasty vs trabeculectomy | RR 2.12 [1.44, 3.11] | NR | Low Downgraded: risk of bias, imprecision, inconsistency |
Failure to stabilise visual field progression (as defined by study investigators) Laser trabeculoplasty vs trabeculectomy | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision, inconsistency |
Failure to stabilise optic neuropathy progression (as defined by study investigators) Laser trabeculoplasty vs trabeculectomy | no estimate extracted | NR | No studies |
Quality of life Laser trabeculoplasty vs trabeculectomy | no estimate extracted | NR | No studies |
Adverse effectsPAS formation Laser trabeculoplasty vs trabeculectomy | RR 1.78 | NR | Very low Downgraded: risk of bias, imprecision, inconsistency |
Adverse effects: IOP spikes Laser trabeculoplasty vs trabeculectomy | RR 1.78 | NR | Very low Downgraded: risk of bias, imprecision, inconsistency |