Cochrane · systematic review · CD004918

Aqueous shunts for glaucoma

Tseng, VL, Coleman, AL, Chang, MY, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
30
current version
GRADE rated
15
No studies
15
Included studies
NR
No studies 15 · 50%Ungraded 0 · 0%Very low 7 · 23.3%Low 5 · 16.7%Moderate 3 · 10%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Aqueous shunts versus trabeculectomy

Population: People with glaucoma
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mean IOP at 1‐year
Aqueous shunts vs trabeculectomy
MD 2.553 studies · 380 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Mean logMAR visual acuity at 1‐year
Aqueous shunts vs trabeculectomy
MD 0.123 studies · 380 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Mean change in visual field score from baseline at 1‐year
Aqueous shunts vs trabeculectomy
no estimate extracted2 studies · 196 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Mean number of antiglaucoma medications at 1‐year
Aqueous shunts vs trabeculectomy
MD 0.8 [0.48, 1.12]1 study · 184 participantsLow
Downgraded: risk of bias, publication bias
Proportion needing additional glaucoma surgery at 1‐year
Aqueous shunts vs trabeculectomy
RR 0.24 [0.04, 1.36]2 studies · 329 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Adverse events up to 1‐year
Aqueous shunts vs trabeculectomy
RR 0.59 [0.43, 0.81]1 study · 212 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Quality of life at 1‐year
Aqueous shunts vs trabeculectomy
no estimate extractedNRNo studies

Ahmed implant versus Baerveldt implant

Population: People with glaucoma
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mean IOP at 1‐year
Ahmed implant vs Baerveldt implant
MD 2.62 studies · 464 participantsModerate
Downgraded: risk of bias
Mean logMAR visual acuity at 1‐year
Ahmed implant vs Baerveldt implant
no estimate extracted2 studies · 501 participantsLow
Downgraded: risk of bias, imprecision
Mean change in visual field score from baseline at 1‐year
Ahmed implant vs Baerveldt implant
no estimate extractedNRNo studies
Mean number of antiglaucoma medications at 1‐year
Ahmed implant vs Baerveldt implant
MD 0.35 [0.11, 0.59]2 studies · 464 participantsModerate
Downgraded: risk of bias
Proportion needing additional glaucoma surgery at 1‐year
Ahmed implant vs Baerveldt implant
RR 2.77 [1.02, 7.54]2 studies · 514 participantsModerate
Downgraded: risk of bias
Adverse events up to 1‐year
Ahmed implant vs Baerveldt implant
no estimate extractedNRNo studies
Quality of life at 1‐year
Ahmed implant vs Baerveldt implant
no estimate extractedNRNo studies

Ahmed implant versus Molteno implant

Population: People with glaucoma
8 questions
OutcomeEffectEvidenceStatus / GRADE
Outcomes*
Ahmed implant vs Molteno implant
no estimate extractedNRNo studies
Mean IOP at 1‐year
Ahmed implant vs Molteno implant
MD 1.641 study · 57 participantsLow
Downgraded: risk of bias, indirectness
Mean logMAR visual acuity at 1‐year
Ahmed implant vs Molteno implant
MD 0.081 study · 57 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Mean change in visual field score from baseline at 1‐year
Ahmed implant vs Molteno implant
no estimate extracted1 study · 57 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Mean number of antiglaucoma medications at 1‐year
Ahmed implant vs Molteno implant
no estimate extracted1 study · 57 participantsLow
Downgraded: risk of bias, indirectness
Proportion needing additional glaucoma surgery at 1‐year
Ahmed implant vs Molteno implant
no estimate extractedNRNo studies
Adverse events up to 1‐year
Ahmed implant vs Molteno implant
no estimate extractedNRNo studies
Quality of life at 1‐year
Ahmed implant vs Molteno implant
no estimate extractedNRNo studies

Molteno implant versus Schocket shunt

Population: People with glaucoma
8 questions
OutcomeEffectEvidenceStatus / GRADE
Outcomes*
Molteno implant vs Schocket shunt
no estimate extractedNRNo studies
Mean IOP at 1‐year
Molteno implant vs Schocket shunt
no estimate extracted1 study · 115 participantsLow
Downgraded: risk of bias, indirectness
Mean logMAR visual acuity at 1‐year
Molteno implant vs Schocket shunt
no estimate extractedNRNo studies
Mean change in visual field score from baseline at 1‐year
Molteno implant vs Schocket shunt
no estimate extractedNRNo studies
Mean number of antiglaucoma medications at 1‐year
Molteno implant vs Schocket shunt
no estimate extractedNRNo studies
Proportion needing additional glaucoma surgery at 1‐year
Molteno implant vs Schocket shunt
no estimate extractedNRNo studies
Adverse events up to 1‐year
Molteno implant vs Schocket shunt
no estimate extractedNRNo studies
Quality of life at 1‐year
Molteno implant vs Schocket shunt
no estimate extractedNRNo studies