Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

219 questions · 223 findings · 25 reviews · Eyes and Vision

No studies found 76 · 34.1%GRADE not reported 5 · 2.2%Very low 39 · 17.5%Low 75 · 33.6%Moderate 25 · 11.2%High 3 · 1.3%

Non‐pharmaceutical interventions vs control

Final visual acuity between 20/20 and 20/50; monocular vs binocular eye patching · people with traumatic hyphema

Non‐pharmaceutical interventions showed no clear difference in final visual acuity between 20/20 and 20/50; monocular vs binocular… compared with control (low certainty).

1 finding from 1 review

Non‐pharmaceutical interventions vs control

Risk of secondary hemorrhage; monocular versus binocular eye patching · people with traumatic hyphema

Non‐pharmaceutical interventions showed no clear difference in risk of secondary hemorrhage; monocular vs binocular eye patching compared with control (low certainty).

1 finding from 1 review

Botulinum toxin vs surgery

Proportion of participants who achieved binocular single vision at 6 or 12 months · adults and children with strabismus

Botulinum toxin showed no clear difference in proportion of participants who achieved binocular single vision at 6… compared with surgery (low certainty).

1 finding from 1 review

Patching vs active observation

Minor adverse events Defined as any adverse event within 8 weeks of surgery that does not require further intervention · people with intermittent exotropia, aged less than 11 years

The review found no eligible studies for this question.

1 finding from 1 review

Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Minor adverse events Defined as any adverse event within 8 weeks of surgery that does not require further intervention · people with intermittent exotropia, aged 3 to < 11 years

Bilateral lateral rectus recession showed no clear difference in minor adverse events Defined as any adverse event within 8 weeks of… compared with unilateral lateral rectus recession with medial rectus resection (low certainty).

1 finding from 1 review

Vitrectomy vs scleral buckling

Adverse effects (cataract development, choroidal detachment, new/iatrogenic breaks, postoperative proliferative vitreoretinopathy, postoperative increase in intraocular pressure, development of cystoid macular oedema, macular pucker, strabismus) a... · people with simple rhegmatogenous retinal detachments

Pars plana vitrectomy (PPV) may leads to higher adverse effects (cataract development, choroidal detachment,… compared with scleral buckling (low certainty).

1 finding from 1 review