Cochrane · systematic review · CD008428
Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Schwartz, SG, Wang, X, Chavis, P, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Vitamin A and fish oils (docosahexaenoic acid) compared to placebo, vitamins (including vitamin A), or no therapy for retinitis pigmentosa
Population: retinitis pigmentosa
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Visual field sensitivity (visual field) Vitamin A and fish oils (docosahexaenoic acid) vs placebo, vitamins (including vitamin A), or no therapy | no estimate extracted | 4 studies · 881 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Visual acuitychange in logMAR visual acuity, may be reported as ETDRS Vitamin A and fish oils (docosahexaenoic acid) vs placebo, vitamins (including vitamin A), or no therapy | no estimate extracted | 4 studies · 881 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Electroretinography (ERG) Vitamin A and fish oils (docosahexaenoic acid) vs placebo, vitamins (including vitamin A), or no therapy | no estimate extracted | 4 studies · 881 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Optical coherence tomography (OCT) Vitamin A and fish oils (docosahexaenoic acid) vs placebo, vitamins (including vitamin A), or no therapy | no estimate extracted | 1 study · 51 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Adverse effects: as reported by studies Vitamin A and fish oils (docosahexaenoic acid) vs placebo, vitamins (including vitamin A), or no therapy | no estimate extracted | 4 studies · 944 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |