Cochrane · systematic review · CD004917

Interventions for infantile esotropia

Mehner, L, Ng, SM, Singh, J · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 0 · 0%Very low 5 · 83.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Surgery versus botulinum neurotoxin injections

Population: children with infantile esotropia
3 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment success: improvement in the angle of strabismus at 6 months
Surgery vs botulinum neurotoxin injections
RR 1.88 [1.27, 2.77]1 study · 101 participantsVery low
Downgraded: risk of bias, imprecision
Presence and quality of binocularity at 6 months
Surgery vs botulinum neurotoxin injections
no estimate extractedNRNo studies
Adverse effects (severe, minor) in 6 months
Surgery vs botulinum neurotoxin injections
no estimate extracted1 study · 101 participantsVery low
Downgraded: risk of bias, imprecision

Bilateral recession versus unilateral recession‐resection

Population: children with infantile esotropia
3 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment success: improvement in the angle of strabismus at 6 months
Bilateral recession vs unilateral recession‐resection
no estimate extracted1 study · 118 participantsVery low
Downgraded: risk of bias, imprecision
Presence and quality of binocularity at 6 months
Bilateral recession vs unilateral recession‐resection
no estimate extracted1 study · 1 participantsVery low
Downgraded: risk of bias, imprecision
Adverse effects (severe, minor) at 6 months
Bilateral recession vs unilateral recession‐resection
no estimate extracted1 study · 118 participantsVery low
Downgraded: risk of bias, imprecision