Change in Mutans streptococci (MS) count in dental plaque · healthy people
Xylitol significantly reduced Mutans streptococci in dental plaque compared with no treatment (SMD -0.73, 95% CI -1.09 to -0.37; 5 trials, I2=53%; not GRADE-rated).
1 finding from 1 review
Poor (inadequate) oral hygiene (prevalence) · Children (<18 years) with intellectual and developmental disabilities (IDD) in India
Poor oral hygiene affects about 38% of children with IDD in India (pooled prevalence 0.38, 95% CI 0.21-0.59; high heterogeneity; ungraded).
1 finding from 1 review
Treatment success (caries lesion arrest or restoration survival) · Patients with deep carious lesions in permanent (mainly posterior) teeth
Minimally invasive caries removal showed a marginally higher mean restoration success rate than conventional removal (83.6% vs 75.4%), but the difference was not statistically significant (Mann-Whitney U, p > 0.05); certainty of evidence was not graded.
1 finding from 1 review
Mean success-rate percentage (unweighted study-level mean, 7 studies) MIT 83.6% vs CT 75.4% (Mann-Whitney U = 0.2, p > 0.05; not statistically significant)
7 studies · 1305 participants
GRADE not reported
Dental caries in permanent teeth · Nigerian individuals with permanent dentition (approximately 12 years and older)
In permanent dentition, high-frequency sugar consumption was associated with non-significant 15% higher odds of caries (OR 1.15, 95% CI 0.88 to 1.52), with no heterogeneity (I2=0%; ungraded).
1 finding from 1 review
Proportion of teeth with non-carious cervical lesions (NCCLs) in ancient skulls · Ancient/prehistoric human skulls (excavated/archaeological skeletal remains)
Non-carious cervical lesions affected a pooled proportion of about 0.4% of teeth in ancient skulls (4 studies; ungraded, very high heterogeneity I2=97.6%).
1 finding from 1 review
Dental caries prevalence · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)
Overweight may make little or no difference to the odds of caries in the permanent dentition (very low certainty).
1 finding from 1 review
Intra-examiner reliability · Children and adults with primary or permanent dentition
Intra-examiner kappa statistics ranged from 0.52 to 1.00 across 6 studies; no meta-analysis or GRADE rating was reported.
1 finding from 1 review
no estimate extracted
6 studies
GRADE not reported
Inter-examiner reliability · Children and adults with primary or permanent dentition undergoing dental caries assessment
Inter-examiner reliability ranged from kappa 0.44 to 0.91 across 13 studies (moderate to almost perfect agreement); certainty not graded.
1 finding from 1 review
Change in Mutans streptococci (MS) count in dental plaque · healthy people
Xylitol reduced Mutans streptococci in dental plaque more than sorbitol (SMD -0.45, 95% CI -0.69 to -0.21; 4 trials, I2=7%); not GRADE-rated.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
MTA and Biodentine have similar pulpotomy success (OR 0.89, not significant; low certainty).
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
TaqI/BglI(rs739837) over-dominant model: TT+GG vs TG was not significantly associated with dental caries (OR 0.89); ungraded.
1 finding from 1 review
Dental caries susceptibility · Institutionalized orphan children (roughly 3 to 18 years)
Primary teeth may carry a higher caries risk than permanent teeth in institutionalized children (RR 1.31), but the difference is not statistically significant (very low certainty).
1 finding from 1 review
Dental caries prevalence · Brazilian children under 5 years in primary dentition (BMI classified by WHO 2006 Z-score)
The evidence is very uncertain about the effect of overweight/obesity on caries odds in the primary dentition (WHO 2006 Z-score; very low certainty).
1 finding from 1 review
OR 0.86 [0.60, 1.22]
3 studies
Very low
Dental caries - SNP-based heritability · Japanese adults (present-study cohort)
SNP-based heritability of dental caries was low (h2=0.0258, SE 0.0155); ungraded.
1 finding from 1 review
Intervention not reported
Overall success (composite of clinical and radiographic success)
1 finding from 1 review
Caries arrestment at the tooth level · Children and adults without systemic diseases affecting dental health
SDF showed a higher caries-free proportion at the tooth level, but the reported difference was not statistically significant.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
Recessive model (CC vs CT+TT) at FokI(rs10735810) showed no significant association with caries (OR 1.23, 95% CI 0.97-1.55); ungraded.
1 finding from 1 review
Dental caries prevalence · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)
The evidence is very uncertain about the effect of obesity on caries odds in the primary dentition (very low certainty).
1 finding from 1 review
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, extraction before age 8 (vs after 10) increases odds of space closure (OR 5.01; low certainty).
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
ApaI(rs7975232) over-dominant model: CC+AA vs CA was not significantly associated with dental caries (OR 0.91); ungraded.
1 finding from 1 review