Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,888 questions · 2,009 findings · 352 reviews

No studies found 224 · 11.1%GRADE not reported 265 · 13.2%Very low 551 · 27.4%Low 540 · 26.9%Moderate 311 · 15.5%High 118 · 5.9%

CBT plus standard care vs usual care

Satisfaction with treatment: 1. Leaving the study early ‐ long term · patients with schizophrenia

COMPARISON 1: CBT+ STANDARD CARE showed no clear difference in satisfaction with treatment: 1. Leaving the study early ‐ long term compared with STANDARD CARE ALONE (moderate certainty).

1 finding from 1 review

CBT vs ALL OTHER PSYCHOLOGICAL THERAPIES

Satisfaction with treatment: leaving the study early Endpoint data (events) · patients with schizophrenia

CBT may leads to lower satisfaction with treatment ‐ leaving the study early for any reason compared with ALL OTHER PSYCHOLOGICAL THERAPIES (low certainty).

1 finding from 1 review

RISPERIDONE vs OLANZAPINE

Leaving the study early · people with both severe mental illness and substance misuse

It is very uncertain whether RISPERIDONE changes leaving study early: any reason compared with OLANZAPINE ‒ short‐ and long‐term data (very low certainty).

1 finding from 1 review

RISPERIDONE vs QUETIAPINE

Leaving the study early · people with both severe mental illness and substance misuse

RISPERIDONE showed no clear difference in leaving the study early: 1. any reason, long term (>12 months) compared with QUETIAPINE ‒ short‐ and long‐term data (low certainty).

1 finding from 1 review

RISPERIDONE vs ZIPRASIDONE ‒ long‐term data (> 12 months)

Leaving the study early · people with both severe mental illness and substance misuse

RISPERIDONE showed no clear difference in leaving the study early: any reason compared with ZIPRASIDONE ‒ long‐term data (> 12 months) (low certainty).

1 finding from 1 review

RISPERIDONE vs CLOZAPINE ‐ all data short term

Leaving the study early · people with both severe mental illness and substance misuse

It is very uncertain whether RISPERIDONE changes leaving the study early ‒ any reason compared with CLOZAPINE ‐ all data short term (very low certainty).

1 finding from 1 review

Laparoscopic retroperitoneal adrenalectomy vs laparoscopic transperitoneal adrenalectomy

Early morbidity (any complication during the first 30 to 60 days following surgery)

It is very uncertain whether laparoscopic retroperitoneal adrenalectomy changes early morbidity (any complication during the first 30 to 60 days… compared with laparoscopic transperitoneal adrenalectomy (very low certainty).

1 finding from 1 review

Absorbable vs non‐absorbable sutures

Postoperative pain: early pain (10 days postoperatively) VAS 0 to 10 Verbal reporting scale No pain‐mild pain‐moderate pain‐severe pain (converted to numerical scale (0 to 3, 3 to 6, 6 to 10)
2 findings from 1 review

Antipsychotic dose increase vs antipsychotic dose continuation

Adverse effects – leaving the study early due to adverse effects – overall tolerability – total · non response in schizophrenia

It is very uncertain whether antipsychotic dose increase changes leaving the study early: tolerability ‐ leaving early due to adverse… compared with antipsychotic dose continuation (very low certainty).

1 finding from 1 review

Antipsychotic dose increase vs antipsychotic dose continuation

Acceptability of treatment ‐ leaving the study early · non response in schizophrenia

Antipsychotic dose increase showed no clear difference in leaving the study early: acceptability ‐ leaving early due to any… compared with antipsychotic dose continuation (low certainty).

1 finding from 1 review

Summary of findings. Below‐elbow vs above‐elbow cast

'Treatment failure': secondary procedures such as remanipulation for early loss of position (only data for this used here); and change in treatment ( · children with either displaced distal radius fracture with intact or displaced ulna fracture (both‐bone fracture), or minimally displaced…

It is very uncertain whether summary of findings. Below‐elbow changes 'Treatment failure': secondary procedures such as remanipulation for… compared with above‐elbow cast (very low certainty).

1 finding from 1 review

Summary of findings. Surgery (percutaneous wire fixation) vs not surgery (cast only)

'Treatment failure': various secondary procedures such as remanipulation for early loss of position; early or more complex wire removal ( · children with displaced distal radius fracture with intact or involved or displaced ulna fracture (both‐bone fracture)

It is very uncertain whether summary of findings. Surgery (percutaneous wire fixation) changes 'Treatment failure': various secondary procedures such as… compared with not surgery (cast only) (very low certainty).

1 finding from 1 review