RISPERIDONE vs CLOZAPINE ‐ all data short term: Leaving the study early
- Population
- people with both severe mental illness and substance misuse
- Intervention
- RISPERIDONE
- Comparison
- CLOZAPINE ‐ all data short term
- Outcome
- Leaving the study early
It is very uncertain whether RISPERIDONE changes leaving the study early ‒ any reason compared with CLOZAPINE ‐ all data short term (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
RISPERIDONE vs CLOZAPINE ‐ all data short term Leaving the study early ‒ any reason · for people with serious mental illness and co‐occurring substance misuse It is very uncertain whether RISPERIDONE changes leaving the study early ‒ any reason compared with CLOZAPINE ‐ all data short term (very low certainty). Risperidone versus other antipsychotics for people with severe mental illness and co‐occurring substance… (2018) · Cochrane Headline outcomes only | RR 0.49 [0.1, 2.51] | 2 studies · 45 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Risperidone versus other antipsychotics for people with severe mental illness and co‐occurring substance misuse 2018 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- RISPERIDONE vs OLANZAPINE · people with both severe mental illness and substance misuse · 1 review
- RISPERIDONE vs ZIPRASIDONE ‒ long‐term data (> 12 months) · people with both severe mental illness and substance misuse · 1 review
- RISPERIDONE vs QUETIAPINE · people with both severe mental illness and substance misuse · 1 review
- RISPERIDONE vs PERHENAZINE ‒ long‐term data · people with both severe mental illness and substance misuse · 1 review
- RISPERIDONE vs placebo · patients with schizophrenia · 0 reviews
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.