Oral mucositis (any severity) · Adults receiving chemotherapy alone for colorectal cancer
Transforming growth factor-beta(2) (TGF-beta2) showed no clear difference in oral mucositis (any severity) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Adults receiving chemotherapy alone for colorectal cancer
Intestinal trefoil factor (ITF), oral spray led to lower oral mucositis (any severity) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Adults with cancer receiving treatment
1 finding from 1 review
Any adverse effect · molluscum contagiosum
Imiquimod showed no clear difference in any adverse effect compared with vehicle (high certainty).
1 finding from 1 review
Death from any cause · patients with hypertension
Enalapril plus folic acid showed no clear difference in death from any cause compared with enalapril (high certainty).
1 finding from 1 review
Adverse reactions to treatment Proportion of participants with adverse reactions to treatment · People with recurrent erysipelas or cellulitis
Antibiotic prophylaxis showed no clear difference in any adverse reactions compared with no treatment/placebo (low certainty).
1 finding from 1 review
Malignancy · people with primary sclerosing cholangitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Unscheduled visits 1 or more hospitalisations for any cause WMD of · children with asthma
School‐based ICS therapy showed no clear difference in unscheduled visits 1 or more hospitalisations for any cause WMD of compared with home therapy (low certainty).
1 finding from 1 review
Oral mucositis (any severity) · Adults receiving chemotherapy alone for colorectal cancer
1 finding from 1 review
Oral mucositis (any severity) · Adults receiving bone marrow/stem cell transplantation after conditioning therapy for haematological cancers
Erythropoietin mouthwash led to lower oral mucositis (any severity) compared with placebo; GRADE not reported.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Corruption Pharmaceutical company spending on gifts · a) pharmaceutical companies, b) community health centre staff, c) health service users
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Condom use: any unprotected sex in past 2 weeks · women with need for family planning (FP)
The intervention leads to lower condom use: any unprotected sex in past 2 weeks (high certainty).
1 finding from 1 review
OR 0.56 [0.32, 0.99]
18 participants
High
Leaving the study early · adults with panic disorder
All psychological therapies showed no clear difference in dropouts for any reason compared with other antidepressants (low certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
It is very uncertain whether all psychological therapies changes dropouts for any reason compared with benzodiazepines (very low certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
It is very uncertain whether all psychological therapies changes dropouts for any reason compared with antidepressants alone or antidepressants and benzodiazepines (very low certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
All psychological therapies showed no clear difference in dropouts for any reason compared with SSRI (low certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
All psychological therapies showed no clear difference in dropouts for any reason compared with tricyclic antidepressants (low certainty).
1 finding from 1 review
Pain ‐ Any grade · women with usual‐type vulval intraepithelial neoplasia
Summary of findings for imiquimod showed no clear difference in pain ‐ any grade compared with cidofovir (moderate certainty).
1 finding from 1 review