Imiquimod vs cidofovir: Pain ‐ Any grade
- Population
- women with usual‐type vulval intraepithelial neoplasia
- Intervention
- Imiquimod
- Comparison
- cidofovir
- Outcome
- Pain ‐ Any grade
Summary of findings for imiquimod showed no clear difference in pain ‐ any grade compared with cidofovir (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings for imiquimod vs cidofovir Pain ‐ any grade · women with usual‐type vulval intraepithelial neoplasia Summary of findings for imiquimod showed no clear difference in pain ‐ any grade compared with cidofovir (moderate certainty). Medical and surgical interventions for the treatment of usual‐type vulval intraepithelial neoplasia (2016) · Cochrane Headline outcomes only | RR 1.16 [0.92, 1.47] | 1 study · 168 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Medical and surgical interventions for the treatment of usual‐type vulval intraepithelial neoplasia 2016 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Imiquimod vs placebo · women with high‐grade VIN · 1 review
- Imiquimod vs placebo · women with usual‐type vulval intraepithelial neoplasia · 1 review
- Imiquimod vs cidofovir · women with high‐grade VIN · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.