Question · asked by 1 review

Intestinal trefoil factor (ITF), lower dose (336 mg) vs Intestinal trefoil factor (ITF), higher dose (2688 mg): Oral mucositis (any severity)

Population
Adults receiving chemotherapy alone for colorectal cancer
Intervention
Intestinal trefoil factor (ITF), lower dose (336 mg)
Comparison
Intestinal trefoil factor (ITF), higher dose (2688 mg)
Outcome
Oral mucositis (any severity)

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Intestinal trefoil factor (ITF), lower dose (336 mg) vs Intestinal trefoil factor (ITF), higher dose (2688 mg)
Oral mucositis (any severity) · Adults receiving chemotherapy alone for colorectal cancer
Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and… (2017) · Cochrane All outcomes
Insufficient evidence to determine whether lower (336 mg) or higher (2688 mg) dose performs better (Analyses 11.1 to 11.3); no pooled estimate reported1 study · 66 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors
2017 · Cochrane All outcomes
2017-05Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.